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Assessing the ability of polysaccharides extracted from date palm fruit to salvage Wistar rats from cisplatin-linked hepatic damage

open access: gold
Omowumi Oyeronke Adewale   +3 more
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Mechanistic Fingerprints from Chloride to Iodide: Halide vs. Ammonia Release in Platinum Anticancer Complexes. [PDF]

open access: yesInt J Mol Sci
Chiaverini L   +14 more
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Cisplatin

Essays in Biochemistry, 1999
Cisplatin is a widely used anti-cancer drug that is exceptionally effective against testicular cancer. trans-DDP, the geometric isomer of cisplatin, is ineffective as a chemotherapeutic agent. The anti-tumour activity of cisplatin is generally attributed to its formation of DNA adducts, both intrastrand and interstrand crosslinks, which induce ...
E E, Trimmer, J M, Essigmann
openaire   +2 more sources

Cisplatin nephrotoxicity

Toxicology Letters, 1989
Cisplatin is used widely in the treatment of a large number of carcinomas. The clinical use of cisplatin, however, can be complicated by myelotoxicity, ototoxicity and intestinal toxicity; we review briefly cisplatin nephrotoxicity. The principal route of its excretion is via the kidney, and accumulation of cisplatin in the renal cortex has been ...
J P, Fillastre, G, Raguenez-Viotte
openaire   +2 more sources

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