Results 161 to 170 of about 104,183 (265)

DTX3L promotes ovarian cancer progression and cisplatin resistance by activating JAK1/STAT1/OAS3 pathway. [PDF]

Sci Rep
Lu F, Zhou Y, Wei Y, Mo S, Tan J, Kuang Y.   +5 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

NAT10 promotes cisplatin resistance and immune escape by increasing the expression of DUSP1 and PD-L1 in gastric cancer. [PDF]

Cell Death Discov
Qian L, Gao W, Wang X, Cui S, Han X, Xu X, Jia J, Liu Z.   +7 more
europepmc   +1 more source

Cisplatin resistance reversal by disulfiram and caffeine

Journal of Pharmacology and Pharmacotherapeutics, 2016
Kadia, Ashish R., Shah, Gaurang B.
openaire   +3 more sources

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Targeting epigenetic networks to overcome cisplatin resistance in ovarian cancer: from mechanisms to clinical translation. [PDF]

J Ovarian Res
Tang M, Wang Y, Xie Y, Li J, Ding D, Li C, Chen Q, Han F.   +7 more
europepmc   +1 more source

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü, Münevver Baran, Miyase Gözde Gündüz, Şengül Dilem Doğan   +3 more
wiley   +1 more source

Correction: CLC3 regulates V-ATPase to enhance lysosomal degradation and cisplatin resistance in cervical cancer cells. [PDF]

Cell Death Discov
Chen C, Zhang F, Shen J, Zheng Q, Zhang Z, Lu S, Liu L, Zhu T, Du Y, Guan Y.   +9 more
europepmc   +1 more source

Discriminating Chemoresistant and Chemosensitive Tubo‐Ovarian High‐Grade Serous Carcinoma Cells With Raman Microscopy

Journal of Raman Spectroscopy, EarlyView.
Confocal Raman microscopy combined with multivariate analysis distinguishes cisplatin‐resistant and ‐sensitive tubo‐ovarian high‐grade serous carcinoma cell lines. ABSTRACT Chemoresistance is a major obstacle to effective cancer treatment, particularly in tubo‐ovarian high‐grade serous carcinoma (HGSC), the most lethal gynaecological malignancy ...
Elina Harju, Parisa Movahedi, Teemu Tomberg, Sara J. Fraser‐Miller, Francesco Piga, Jukka Saarinen, Kathleen J. Sircombe, Jacopo Zini, Jukka Heikkonen, Anna Laury, Sarah Hook, Keith C. Gordon, Tapio Pahikkala, Clare J. Strachan   +13 more
wiley   +1 more source

JPH3 Facilitates Cisplatin Resistance in Anaplastic Thyroid Cancer via Activation of the JAK-STAT Signaling Pathway. [PDF]

Cancer Med
Wang X, Luan S, Sun L, Lian L, Qi M.
europepmc   +1 more source