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Preparation, physicochemical properties of Cistanche deserticola polysaccharides and their bidirectional immunomodulatory activity analysis using Caco-2 cell models.

Food Research International
This study compared the physicochemical properties and immune activity in vitro of Cistanche deserticola polysaccharides prepared by different drying methods (freeze-drying and hot-air-drying) and from different sampling parts (flesh and peel).
Weijie Wang   +8 more
semanticscholar   +1 more source

Studies on the sedative effect of Cistanche deserticola

Journal of Ethnopharmacology, 1998
In this study, we investigated the sedative effect of Cistanche deserticola Ma. (CD) on hexobarbital-induced sleeping time in mice and spontaneous motor activity by using automated activity meter in rats. It was found that crude extract of CD could prolong the hexobarbital-induced sleeping time and reduce spontaneous motor activity, including ...
openaire   +2 more sources

Neuroprotective effect of Cistanche deserticola glycosides in MPTP-Induced Parkinson’s disease mouse model involves Nrf2 activation

Journal of Toxicology and Environmental Health, Part A
Parkinson’s Disease (PD) a progressive neurodegenerative disorder is attributed to dopaminergic neuronal cell loss in the mid-brain substantia nigra pars compacta. A major risk factors associated with PD development is presence of excess oxidative stress.
Shu-Qing Yao   +9 more
semanticscholar   +1 more source

The potential, challenges, and prospects of polysaccharides from the genus Cistanche as therapeutic agents for aging-related diseases: A review.

International Journal of Biological Macromolecules
Cistanche has been utilized globally as both a food and medicinal ingredient for centuries. Modern pharmacological studies have demonstrated that polysaccharides, as the primary active components of Cistanche, exhibit diverse pharmacological activities ...
Jing Tao   +6 more
semanticscholar   +1 more source

Cistanche total glycoside capsule promotes sperm maturation and fertility by activating the NELL2 Lumicrine pathway in a male reproductive impairment model.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE Cistanche deserticola Ma is a traditional Chinese herb for reproductive health. Cistanche total glycoside capsule (CTGC), derived from Cistanche deserticola, is clinically used for the treatment of vascular dementia, yet ...
Li Guo   +7 more
semanticscholar   +1 more source

Cistanche deserticola Polysaccharides Mitigate Alzheimer's Disease Progression by Dynamic Regulation of Gut Microbiota Composition and Metabolites.

The American Journal of Chinese Medicine
Cistanche deserticola polysaccharides (CDPS) exhibit a range of pharmacological activities, most notably in immune modulation, anti-oxidation, and gut microbiota regulation.
Yuan Gao   +10 more
semanticscholar   +1 more source

Cistanche deserticola polysaccharide-functionalized dendritic fibrous nano-silica as oral vaccine adjuvant delivery enhancing both the mucosal and systemic immunity.

International Journal of Biological Macromolecules
Oral vaccines are a safe and convenient alternative to injected vaccines and have great potential to prevent major infectious diseases. However, the harsh gastrointestinal (GI) environment, mucus barriers, low immunogenicity, and lack of effective and ...
Jin He   +8 more
semanticscholar   +1 more source

Hepatoprotective Activity of Phenylethanoids fromCistanche deserticola

Planta Medica, 1998
Four phenylethanoids isolated from the stems of Cistanche deserticola, acteoside (1), 2'-acetylacteoside (2), isoacteoside (3) and tubuloside B (4), significantly suppressed NADPH/CCl4-induced lipid peroxidation in rat liver microsomes. Addition of them to primary cultured rat hepatocytes efficiently prevented cell damage induced by exposure to CCl4 or
Q, Xiong   +5 more
openaire   +2 more sources

Advance in Cistanche deserticola Y. C. Ma. polysaccharides: Isolation, structural characterization, bioactivities and application: A review.

International Journal of Biological Macromolecules
Cistanche deserticola Y. C. Ma (CD), is mainly distributed in the regions of China (Xinjiang, Inner Mongolia, Gansu), Mongolia, Iran and India. Cistanche deserticola polysaccharide (CDPs), as one of the main components and a crucial bioactive substance ...
Tao-Tao Xue   +9 more
semanticscholar   +1 more source

Cistanches herba Induces Testis Cytotoxicity in Male Mice

Bulletin of Environmental Contamination and Toxicology, 2011
We investigated the effects of Cistanches herba (CH) on the male reproductive system in mice, assessing CREM gene expression and spermatogenesis. Our results demonstrate that CH treatment lead to a significant decrease in sperm count dose-dependently, 298.3 ± 48.9 vs. 296.6 ± 102.4 (250 mg/kg), 236.7 ± 75.1 (500 mg/kg), 223.0 ± 48.7 × 10(6) (1000 mg/kg)
San Woong, Kim   +6 more
openaire   +2 more sources

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