Results 281 to 290 of about 5,319,795 (358)

Organization of the Proteostasis Network of Membraneless Organelles

Advanced Science, EarlyView.
A comprehensive mapping of the proteostasis network (PN) across membraneless organelles (MLOs) reveals how central PN components coordinate MLO regulation. The analysis uncovers principles of specificity and promiscuity within the PN. The findings suggest that HSP70 chaperones act as generic MLO regulators, while client specific HSP70 co‐chaperones may
Christine M. Lim, Yuqi Bian, Alicia González Díaz, Frank Pun, Alex Zhavoronkov, Richard I. Morimoto, Michele Vendruscolo   +6 more
wiley   +1 more source

Integrating clinical trial landscapes and bibliometric analysis: unveiling the impact of PD-1/PD-L1 inhibitors on renal cell carcinoma research and therapeutic trajectories summary. [PDF]

Front Immunol
Huang Y, Ma X, Zhu H, Shen C, Hu K, Yu Y, Yang A, Liu Z, Liu C, Shi W, Wang W, Xia X, Wang J, Li X.   +13 more
europepmc   +1 more source

Citation classics: most-cited articles from Fertility and Sterility

, 1987
Jack D. Key, Roger D. Kempers
openalex   +1 more source

Toward the Clinical Translation of Implantable Brain–Computer Interfaces for Motor Impairment: Research Trends and Outcome Measures

Advanced Science, EarlyView.
Implantable brain–computer interfaces (iBCIs) are rapidly approaching clinical translation. This review maps key trends in the development of iBCIs and highlights the lack of standardised clinical outcome measures. It discusses a proposed framework for the selection of outcome measures in clinical trials and introduces a new international registry of ...
Esmee Dohle, Eleanor Swanson, Luka Jovanovic, Suraya Yusuf, Lucy Thompson, Hugo Layard Horsfall, William Muirhead, Luke Bashford, Jamie Brannigan   +8 more
wiley   +1 more source

Predicting the unseen: nutritional interventions as a key to combat frailty. [PDF]

Front Nutr
Shi L, Tian X, Bongsook Y, Chen J.
europepmc   +1 more source

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

Advanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan, Han Ma, Jespar Chen, Gaifeng Ma, Alok Jha, Sipin Tan, Yaxi Zhu, Meidong Liu, Ke Liu, Xianzhong Xiao, Monowar Aziz, Huan Chen, Ping Wang, Huali Zhang   +13 more
wiley   +1 more source

Research trends and visualization analysis of autoimmune disease-related liver cancer from 2004 to 2024: a bibliometric study. [PDF]

Discov Oncol
Zhang X, Xie Y, Zhou W, Wang Q, Chen B.
europepmc   +1 more source

Application of Bradford's Law to Citation Data

, 1981
Gloria S. Cline
openalex   +2 more sources

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

Advanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen, Can Chen, Yichen Wu, Yinxue Xia, Ruijie Luo, Jiangcheng Shu, Long Chen, Zhaohui Wang, Cheng Wang, Kai Huang   +9 more
wiley   +1 more source

Citations

BioTechniques, 2006
openaire   +4 more sources