To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Thoracic segmental spinal anaesthesia for scapular fracture: Facts versus exaggerations!! [PDF]
Reena, Rath A.
europepmc +1 more source
Newsroom: PolitiFact Blog Cites Zlotnick on AG Campaign Claims [PDF]
Roger Williams University School of Law
core +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Erratum: Approach to the Evaluation and Management of Interstitial Lung Abnormalities: An Official American Thoracic Society Clinical Statement. [PDF]
europepmc +1 more source
Strengthening the evidence and implementation framework for family medicine in MBBS curriculum. [PDF]
Shaikh S, Khuntia SS, Srivastava K.
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A Scoping Review of Noncommunicable Disease Programs Evaluation: Bridging Gaps and Improving Frameworks in Primary Healthcare. [PDF]
Marvi A +6 more
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Commentary: Health and safety practices and policies concerning human exposure to RF/microwave radiation. [PDF]
Bailey WH, Foster KR, Chou CK.
europepmc +1 more source

