Results 71 to 80 of about 1,390,912 (292)

Anatomic Multiligament Knee Reconstruction With Biceps Femoris Tendon and Medial Meniscal Repair

Video Journal of Sports Medicine
Background: Multiligament knee injuries are defined as tears of ≥2 of the following ligament structures: anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), posteromedial corner, or posterolateral corner (PLC).
Benjiman J. Wilebski MD, ATC, Luke V. Tollefson BS, Dustin R. Lee MD, Matthew T. Rasumussen MD, Robert F. LaPrade MD, PhD   +4 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Folder 4: Little Rock: Program Information - Projects Inventory; Model Cities: Facets of Community Development, undated

, 1972
Pamphlet for the Model Cities: Facets of Community Development for Little Rock, Arkansas. Published by the National Model Cities Community Development Directors Association, National League of Cities in Washington, D. C.
National Model Cities Community Development Directors Association
core   +1 more source

Arthroscopic-Assisted Open Excision of an Infrapatellar Tendon Osgood-Schlatter’s Bony Ossicle

Arthroscopy Techniques
Osgood-Schlatter disease (OSD) is a cumulative traction apophysitis condition caused by microavulsions along the apophysis at the tibial tuberosity and patellar tendon, which sometimes create a protruding bony ossicle at the anterior tibial tubercle ...
Rylan A. Behnke, B.S., Nicholas K. Retzer, B.S., Benjiman J. Wilebski, M.D., A.T.C., Luke V. Tollefson, B.S., Matthew T. Rasmussen, M.D., Dustin R. Lee, M.D., Robert F. LaPrade, M.D., Ph.D.   +6 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Anterior Opening-Wedge Proximal Tibial Osteotomy for Symptomatic Genu Recurvatum and Osteochondral Autograft Transfer for Osteochondral Defect

Arthroscopy Techniques
Acute knee hyperextension injuries are more frequently sustained during athletic trauma and can cause symptomatic pain, soft-tissue laxity of the knee, malalignment, and ligament strain. Decreased posterior tibial slope is correlated with a higher degree
Kennedy P. Bueno, Luke V. Tollefson, B.S., Evan P. Shoemaker, B.A., Erik L. Slette, M.D., Robert F. LaPrade, M.D., Ph.D.   +4 more
doaj   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

CREB5 promotes tumorigenicity and upregulates druggable cell surface modalities in basal-like breast cancer

npj Precision Oncology
Basal-like breast cancers (BLBC) have limited targeted therapies and poor outcomes. We found that CREB5 is a transcription factor overexpressed in 15% of BLBCs and was upregulated in breast cancers that metastasize to the brain.
Allison Makovec, Ella Boytim, Ava Gustafson, Megan Ludwig, Liangjun Wang, Atef Ali, Khalid Ishani, Christine Luo, Hannah E. Bergom, Emily John, Sydney Tape, Samuel Kellen, Aiden Deacon, Fatemah Iman Dewji, Camden Richter, Lauren Cookle, David Moline, Jonathan P. Rennhack, Justin M. Drake, Emmanuel S. Antonarakis, David A. Largaespada, Julie H. Ostrander, Justin Hwang   +22 more
doaj   +1 more source