Results 11 to 20 of about 16,392 (217)

AVALIAÇÃO DE CITOCINAS NA FIBROSE HEPÁTICA INDUZIDA EM RATOS PELA LIGADURA DO DUCTO BILIAR

open access: yesRevista UniVap, 2015
A fibrose hepática é uma doença causada por uma grande variedade de doenças crônicas que afetam o fígado após diferentes agressões, cujo único tratamento é o transplante de fígado.
Juliana Saraiva Freitas   +3 more
doaj   +2 more sources

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

open access: yesVeterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki   +4 more
wiley   +1 more source

CITOCINAS E FATORES DE CRESCIMENTO DO SOBRENADANTE DE CONCENTRADO DE HEMÁCIAS DE SANGUE DE CORDÃO UMBILICAL E DE DOADORES ADULTOS

open access: yesHematology, Transfusion and Cell Therapy, 2023
O Sangue de Cordão Umbilical e Placentário (SCUP) tem se destacado como uma valiosa fonte de citocinas e Fatores de Crescimento (FCs). Neste estudo, o objetivo foi investigar a presença de citocinas e FCs no sobrenadante de concentrado de hemácias obtido
MA Risso, E Deffune, ACM Luzo
doaj   +1 more source

The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis

open access: yesVeterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger   +4 more
wiley   +1 more source

Altered plasma cytokines in dogs with atopic dermatitis

open access: yesVeterinary Dermatology, Volume 33, Issue 2, Page 131-e38, April 2022., 2022
Background – Canine (Canis lupus familiaris) atopic dermatitis (AD) shares similar clinical signs to human AD. The abnormal immune response of AD is orchestrated by T lymphocytes, and may include variable involvement of cytokines, Regulatory T (Treg) cells, eosinophils, mast cells and other immune components.
Hamutal Mazrier   +3 more
wiley   +1 more source

Entorno inflamatorio diferencial en pacientes con osteoporosis y diabetes mellitus tipo 2

open access: yesRevista de Osteoporosis y Metabolismo Mineral, 2022
Objetivo: La diabetes mellitus tipo 2 (DM2) y la osteoporosis son enfermedades asociadas con un entorno pro-inflamatorio, cuya prevención mediante nuevas estrategias terapéuticas podría evitar su desarrollo.
Muñoz-Torres M   +9 more
doaj   +1 more source

Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus

open access: yesVeterinary Dermatology, Volume 32, Issue 6, Page 681-e182, December 2021., 2021
Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck   +6 more
wiley   +1 more source

Citocinas e quimiocinas no transplante renal [PDF]

open access: yesJornal Brasileiro de Nefrologia, 2009
O transplante renal e a melhor modalidade de terapia renal substutiva ate o momento. Infelizmente, a sobrevida do enxerto e interrompida pelos episodios de rejeicao aguda ou mesmo de fibrose intersticial/atrofia tubular. A dosagem de quimiocinas e citocinas urinarias como ferramenta alternativa para o diagnostico dessas complicacoes tem sido relatada ...
Pereira, André Barreto   +4 more
openaire   +3 more sources

Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update

open access: yesVeterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti   +7 more
wiley   +1 more source

Immunopathogenesis of the feline atopic syndrome

open access: yesVeterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell   +3 more
wiley   +1 more source

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