Results 1 to 10 of about 1,802 (69)
Mediators of Inflammation, 2021 Background. Regulatory T cells (Tregs) are important in regulating responses to innocuous antigens, such as allergens, by controlling the Th2 response, a mechanism that appears to be compromised in atopic asthmatic individuals.
C. T. Azevedo +5 more
doaj +2 more sources
The Role of the Adrenal–Gut–Brain Axis on Comorbid Depressive Disorder Development in Diabetes
Biomolecules, 2023 Diabetic patients are more affected by depression than non-diabetics, and this is related to greater treatment resistance and associated with poorer outcomes. This increase in the prevalence of depression in diabetics is also related to hyperglycemia and
Thalita Mázala-de-Oliveira +3 more
doaj +1 more source
Pharmaceutics, 2021 Psychoactive substances during pregnancy and lactation is a key problem in contemporary society, causing social, economic, and health disturbance. In 2010, about 30 million people used opioid analgesics for non-therapeutic purposes, and the prevalence of
Nair C. F. Castro +8 more
doaj +1 more source
Biomedicines, 2023 The influence of black carbon nanoparticles on J774.A1 murine cells was investigated with the objective of exploring the cytotoxicity of black carbon functionalized with ethylenediamine CB-EDA.
Joice Margareth de Almeida Rodolpho +9 more
doaj +1 more source
Endometriosis: A Disease with Few Direct Treatment Options
Molecules, 2022 Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility in addition to high treatment costs.
Patricia Ribeiro de Carvalho França +2 more
doaj +1 more source
Veterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023 Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki +4 more
wiley +1 more source
Equine Veterinary Journal, Volume 55, Issue 3, Page 426-434, May 2023., 2023 Abstract Background Neutrophil gelatinase‐associated lipocalin (NGAL) is produced in response to inflammation in horses, but it has not yet been investigated as a biomarker in horses with the abdominal disease. Objectives To investigate NGAL in serum and peritoneal fluid in horses with the abdominal disease.
Malou F. Winther +3 more
wiley +1 more source
Clinical and Translational Science, Volume 16, Issue 4, Page 631-646, April 2023., 2023 Abstract The severe acute respiratory syndrome coronavirus 2, the agent of the ongoing coronavirus disease 2019 (COVID‐19) pandemic, has spread worldwide since it was first identified in November 2019 in Wuhan, China. Since then, progress in pathogenesis linked severity of this systemic disease to the hyperactivation of network of cytokine‐driven pro ...
Amanda Roberta Revoredo Vicentino +17 more
wiley +1 more source
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 This study is aimed at evaluating the profile of inflammatory markers and components of redox regulation in untrained women after 10 weeks of resistance training using equalized protocols but different muscle action duration (MAD). Twenty‐two women underwent progressive resistance training exercising the knee extensor muscles for 10 weeks—3x/week, with
Kelerson Mauro de Castro Pinto +11 more
wiley +1 more source
Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus
Veterinary Dermatology, Volume 32, Issue 6, Page 681-e182, December 2021., 2021 Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck +6 more
wiley +1 more source