Results 11 to 20 of about 17,814 (169)
Veterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022 Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger +4 more
wiley +1 more source
Altered plasma cytokines in dogs with atopic dermatitis
Veterinary Dermatology, Volume 33, Issue 2, Page 131-e38, April 2022., 2022 Background – Canine (Canis lupus familiaris) atopic dermatitis (AD) shares similar clinical signs to human AD. The abnormal immune response of AD is orchestrated by T lymphocytes, and may include variable involvement of cytokines, Regulatory T (Treg) cells, eosinophils, mast cells and other immune components.
Hamutal Mazrier +3 more
wiley +1 more source
Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus
Veterinary Dermatology, Volume 32, Issue 6, Page 681-e182, December 2021., 2021 Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck +6 more
wiley +1 more source
Citocinas pró-inflamatórias e dor [PDF]
Revista Brasileira de Reumatologia, 2006 Este artigo revisa a interacao entre citocinas, celulas da glia e o mecanismo de dor. O ser vivo e capaz de identificar um estimulo agressivo e memoriza-lo para sua defesa diante de uma nova ameaca, atraves de fenomenos motores de retirada e ativacao do sistema nervoso simpatico.
Kraychete, Durval Campos +2 more
openaire +3 more sources
Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update
Veterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021 Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti +7 more
wiley +1 more source
COVID-19: Compreendendo a “tempestade de citocinas”
Research, Society and Development, 2021 O SARS-CoV-2 espalhou-se rapidamente pela China e logo recebeu atenção mundial, levando a Organização Mundial da Saúde (OMS) a declarar, em 30 de janeiro de 2020, a infecção pelo SARS-CoV-2 como emergência de saúde pública de interesse internacional.
Raffaela Neves Mont'Alverne Napoleão +4 more
openaire +2 more sources
Immunopathogenesis of the feline atopic syndrome
Veterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021 Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell +3 more
wiley +1 more source
Citocinas, integrinas e patogenia da malária [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 1989 35^ ]infocitos T1^ B' e celulas NK2^. Em consequencia, varias citocinas sao produzidas e liberadas por estas celulas, inclusive as interleucinas (IL), interferons (IFN) e fatores de necrose tumoral (FNT), alem de diversos fatores de crescimento. As citocinas, agindo atraves de suas acoes autocrinas e paracrmas, em concentracoes minimas, sao essenciais ...
Tosta, Carlos Eduardo +1 more
openaire +3 more sources
Investigando o Papel Causal das Citocinas Inflamatórias no Desenvolvimento de Doenças Cardiovasculares, Renais e Metabólicas [PDF]
Arquivos Brasileiros de CardiologiaResumo Fundamento Estudos observacionais têm relacionado citocinas inflamatórias a distúrbios cardiometabólicos; no entanto, ainda não está claro se essas associações refletem efeitos causais em sistemas orgânicos interconectados.
Mengjin Hu +3 more
doaj +4 more sources
Citocinas en la patogenia de la enfermedad celíaca [PDF]
Medicina Clínica, 2005 Producción ...
León, Alberto José +2 more
openaire +2 more sources