Results 11 to 20 of about 16,392 (217)
AVALIAÇÃO DE CITOCINAS NA FIBROSE HEPÁTICA INDUZIDA EM RATOS PELA LIGADURA DO DUCTO BILIAR
A fibrose hepática é uma doença causada por uma grande variedade de doenças crônicas que afetam o fígado após diferentes agressões, cujo único tratamento é o transplante de fígado.
Juliana Saraiva Freitas +3 more
doaj +2 more sources
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki +4 more
wiley +1 more source
O Sangue de Cordão Umbilical e Placentário (SCUP) tem se destacado como uma valiosa fonte de citocinas e Fatores de Crescimento (FCs). Neste estudo, o objetivo foi investigar a presença de citocinas e FCs no sobrenadante de concentrado de hemácias obtido
MA Risso, E Deffune, ACM Luzo
doaj +1 more source
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger +4 more
wiley +1 more source
Altered plasma cytokines in dogs with atopic dermatitis
Background – Canine (Canis lupus familiaris) atopic dermatitis (AD) shares similar clinical signs to human AD. The abnormal immune response of AD is orchestrated by T lymphocytes, and may include variable involvement of cytokines, Regulatory T (Treg) cells, eosinophils, mast cells and other immune components.
Hamutal Mazrier +3 more
wiley +1 more source
Entorno inflamatorio diferencial en pacientes con osteoporosis y diabetes mellitus tipo 2
Objetivo: La diabetes mellitus tipo 2 (DM2) y la osteoporosis son enfermedades asociadas con un entorno pro-inflamatorio, cuya prevención mediante nuevas estrategias terapéuticas podría evitar su desarrollo.
Muñoz-Torres M +9 more
doaj +1 more source
Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus
Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck +6 more
wiley +1 more source
Citocinas e quimiocinas no transplante renal [PDF]
O transplante renal e a melhor modalidade de terapia renal substutiva ate o momento. Infelizmente, a sobrevida do enxerto e interrompida pelos episodios de rejeicao aguda ou mesmo de fibrose intersticial/atrofia tubular. A dosagem de quimiocinas e citocinas urinarias como ferramenta alternativa para o diagnostico dessas complicacoes tem sido relatada ...
Pereira, André Barreto +4 more
openaire +3 more sources
Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti +7 more
wiley +1 more source
Immunopathogenesis of the feline atopic syndrome
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell +3 more
wiley +1 more source

