Results 11 to 20 of about 52,293 (211)
Para esta conferencia, en gracia a la brevedad, he escogido los aspectos más relevantes de las Citocinas: Qué y cuáles son, Cuáles son sus principales efectos biológicos, y, Cuál es su utilidad terapéutica en Dermatología.
Jairo Mesa Cock
doaj +1 more source
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki +4 more
wiley +1 more source
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger +4 more
wiley +1 more source
Altered plasma cytokines in dogs with atopic dermatitis
Background – Canine (Canis lupus familiaris) atopic dermatitis (AD) shares similar clinical signs to human AD. The abnormal immune response of AD is orchestrated by T lymphocytes, and may include variable involvement of cytokines, Regulatory T (Treg) cells, eosinophils, mast cells and other immune components.
Hamutal Mazrier +3 more
wiley +1 more source
Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus
Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck +6 more
wiley +1 more source
Citocinas pró-inflamatórias e dor [PDF]
Este artigo revisa a interacao entre citocinas, celulas da glia e o mecanismo de dor. O ser vivo e capaz de identificar um estimulo agressivo e memoriza-lo para sua defesa diante de uma nova ameaca, atraves de fenomenos motores de retirada e ativacao do sistema nervoso simpatico.
Kraychete, Durval Campos +2 more
openaire +3 more sources
Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti +7 more
wiley +1 more source
Immunopathogenesis of the feline atopic syndrome
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell +3 more
wiley +1 more source
Citocinas, integrinas e patogenia da malária [PDF]
35^ ]infocitos T1^ B' e celulas NK2^. Em consequencia, varias citocinas sao produzidas e liberadas por estas celulas, inclusive as interleucinas (IL), interferons (IFN) e fatores de necrose tumoral (FNT), alem de diversos fatores de crescimento. As citocinas, agindo atraves de suas acoes autocrinas e paracrmas, em concentracoes minimas, sao essenciais ...
Tosta, Carlos Eduardo +1 more
openaire +3 more sources
Citocinas en la patogenia de la enfermedad celíaca [PDF]
Producción ...
León, Alberto José +2 more
openaire +2 more sources

