Results 11 to 20 of about 14,862 (209)

Key role for inhibins in effective T cell activation, migration and Th17 differentiation. [PDF]

FEBS Open Bio
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Ortega-Francisco S, Olguín-Alor R, Bolaños-Castro L, Morales-Cruz A, De La Fuente-Granada M, Soldevila G.   +5 more
europepmc   +2 more sources

P732: TH17/TREG IMBALANCE IN LOW RISK MDS PATIENTS

HemaSphere, 2022
HemaSphere, Volume 6, Issue S3, Page 627-628, June 2022.
M. Boada, N. Trias, A. Brugnini, C. Guillermo, S. Grille   +4 more
doaj   +2 more sources

Association between CD20⁺ T lymphocytes and neuropsychological findings in multiple sclerosis. [PDF]

Eur J Neurol
Abstract Background and purpose CD20+ T lymphocytes are a subset of circulating T cells presenting the CD20+ receptor, a molecular marker of B lineage. CD20+ T lymphocytes are thought to play a pivotal role in multiple sclerosis (MS) pathology, especially at progressive stages.
Esposito A, Falco F, Scalia G, Gentile L, Spiezia AL, Corsini G, Manganiello R, Eliano M, Lamagna F, Moccia M, Petracca M, Lanzillo R, Brescia Morra V, Carotenuto A.   +13 more
europepmc   +2 more sources

Downstream process design for Gag HIV‐1 based virus‐like particles

Biotechnology and Bioengineering, Volume 120, Issue 9, Page 2672-2684, September 2023., 2023
Abstract Virus‐like particles‐based vaccines have been gaining interest in recent years. The manufacturing of these particles includes their production by cell culture followed by their purification to meet the requirements of its final use. The presence of host cell extracellular vesicles represents a challenge for better virus‐like particles ...
Elianet Lorenzo, Laia Miranda, Francesc Gòdia, Laura Cervera   +3 more
wiley   +1 more source

Participation of apoptotic markers in the process of maturation and elimination of spermatozoa in the epididymis of the Corynorhinus mexicanus bat

Molecular Reproduction and Development, Volume 90, Issue 8-9, Page 749-757, August-September., 2023
Abstract The Corynorhinus mexicanus bat is characterized by a specific form of reproductive asynchrony between males and females. After mating, some sperm remain in the male's epididymis, the organ where the sperm had matured. It has not yet been determined if apoptotic markers participate in the process of the maturation and/or elimination of these ...
Gihovani Ademir Samano‐Barbosa, Blanca Patrícia López‐Trinidad, Ahiezer Rodríguez‐Tobón, Julio Cesar Chávez‐Zamora, Edith Cortés‐Barberena, Miguel Angel León‐Galván, Ernesto Rodríguez‐Tobón, Edith Arenas‐Ríos   +7 more
wiley   +1 more source

Aging is accompanied by T‐cell stiffening and reduced interstitial migration through dysfunctional nuclear organization

Immunology, Volume 167, Issue 4, Page 622-639, December 2022., 2022
Proposed biophysical model. Abstract Age‐associated changes in T‐cell function play a central role in immunosenescence. The role of aging in the decreased T‐cell repertoire, primarily because of thymic involution, has been extensively studied. However, increasing evidence indicates that aging also modulates the mechanical properties of cells and the ...
Blanca González‐Bermúdez, Hikaru Kobayashi, Aldo Abarca‐Ortega, Miguel Córcoles‐Lucas, Mónica González‐Sánchez, Mónica De la Fuente, Gustavo V. Guinea, Manuel Elices, Gustavo R. Plaza   +8 more
wiley   +1 more source

LINFOPENIA T CD4 NO LUPUS ERITEMATOSO SISTÉMICO [PDF]

, 2009
: Background: Systemic Lupus Erythematosus (SLE) is an inflammatory chronic disease characterized by the presence of autoantibodies, immunocomplex production and organ injury.
Almeida, I., Barbosa, P., Correia, J., Farinha, F., Ferreira, S., Marinho, A., Mendonça, T., Vasconcelos, C., Vasconcelos, J.   +8 more
core   +2 more sources

CD30 NEGATIVE/CD4 POSITIVE CYTOTOXIC T CELL LYMPHOMA: A RARE CUTANEOUS LYMPHOPROLIFERATIVE DISORDER

Hematology, Transfusion and Cell Therapy, 2023
Introduction: There are few reports of primary cutaneous lymphomas with CD4 + / CD30 negative cytotoxic T cell immunophenotype. Primary CD30 negative cutaneous T lymphomas are rare and correspond to less than 5% of all cutaneous T-lymphomas.
Lais Pereira, Luiz Gustavo Rodrigues Barbosa, Camila Marques Bertolucci, Alef Rafael Severino, Marcia Higashi, Ederson Roberto de Mattos, Maura Rosane Valerio Ikoma-Colturato   +6 more
doaj   +1 more source

Mastocytosis presenting with mast cell‐mediator release‐associated symptoms elicited by cyclo oxygenase inhibitors: prevalence, clinical, and laboratory features

Clinical and Translational Allergy, Volume 12, Issue 3, March 2022., 2022
Abstract Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are frequently avoided in mastocytosis, because of a potential increased risk for drug hypersensitivity reactions (DHRs) due to inhibition of cyclo‐oxygenase (COX), subsequent depletion of prostaglandin E2 and release of leukotrienes.
Tiago Azenha Rama, José Mário Morgado, Ana Henriques, Luis Escribano, Iván Alvarez‐Twose, Laura Sanchez‐Muñoz, André Moreira, José Romão, Alberto Órfão, Almudena Matito   +9 more
wiley   +1 more source

PERFORMANCE DO DXFLEX NO TESTE DE CROSSMATCH POR CITOMETRIA DE FLUXO

Hematology, Transfusion and Cell Therapy, 2023
Objetivo: Demonstrar a validação e a performance da plataforma de citometria de fluxo DxFlex (Beckman Coulter) no teste de crossmatch por CF pelo protocolo Halifaster, em comparação com a plataforma FACS CANTO II (Becton Dickinson – BD).
LC Bento, FA Sousa, JFD Nacimento, VGS Teixeira, TM Valim, MA Torres, EX Souto, NS Bacal   +7 more
doaj   +1 more source