Results 141 to 150 of about 540,533 (312)

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source

A Perspective on the Applications of Triphasic Gas Storage in Electrochemical Systems

Advanced Science, EarlyView.
Gas storage in microporous materials positioned locally at an electrode or electrocatalyst surface enhances electrochemical processes. Abstract Microporous materials store gases under dry conditions (e.g., hydrogen or oxygen via physisorption), but in some cases microporous materials also show triphasic (e.g., in a solid|gas|liquid system) gas storage ...
Zhongkai Li, Corin T. Scott, Taku Suzuki‐Osborne, John P. Lowe, Dominic Taylor, Mariolino Carta, Neil B. McKeown, Andrew D. Burrows, Lucia H. Mascaro, Frank Marken   +9 more
wiley   +1 more source

Phosphorus acquisition by citrate- and phytase-exuding Nicotiana tabacum plant mixtures depends on soil phosphorus availability and root intermingling

, 2018
Citrate and phytase root exudates contribute to improved phosphorus (P) acquisition efficiency in Nicotiana tabacum (tobacco) when both exudates are produced in a P deficient soil.
Shand, Charles A., Lawrie K. Brown, Cade-Menun, Barbara J., Hao Zhang, Stutter, Marc I., Brown, L. K., Stutter, M. I., Marc I. Stutter, Barbara J. Cade-Menun, Tegan Darch, Alan E. Richardson, Catherine Wearing, Brown, Lawrie K., David G. Lumsdon, Zhang, H., Courtney D. Giles, Cade-Menun, B. J., Giles, Courtney D., Cooper, Patricia, Blackwell, M. S. A., Shand, C. A., Darch, T., Richardson, Alan E., Zhang, Hao, Darch, Tegan, Wearing, Catherine, Giles, C. D., Menezes-Blackburn, Daniel, Menezes-Blackburn, D., Daniel Menezes-Blackburn, Patricia Cooper, Timothy S. George, Richardson, A. E., Lumsdon, D. G., Haygarth, Philip M., Blackwell, Martin S.A., Cooper, P., George, Timothy S., Wendler, R., Malika M. Mezeli, George, T. S., Philip M. Haygarth, Haygarth, P. M., Wearing, C., Martin S.A. Blackwell, Lumsdon, David G., Renate Wendler, Charles A. Shand, Mezali, M. M., Wendler, Renate, Mezeli, Malika M.   +50 more
core   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Pacritinib Citrate

American Journal of Health-System Pharmacy, 2022
openaire   +2 more sources

Citrate anticoagulation for extracorporeal circuits: Effects on whole blood coagulation activation and clot formation [PDF]

, 2001
Calatzis, A., Schramm, W., Schiffl, Helmut, Toepfer, Marcel, Spannagl, M.   +4 more
core   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Renal citrate metabolism and urinary citrate excretion in the infant rat

, 2000
Renal citrate metabolism and urinary citrate excretion in the infant rat.BackgroundAlthough hypercalciuria has the same prevalence in children as adults, children rarely develop renal stones.
Melnick, Joel Z., Preisig, Patricia A., Alpern, Robert J., Baum, Michel   +3 more
core   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Citrate: Valence and Milliequivalent Considerations

, 1995
Objective: To demonstrate that an understanding of the valence of citrate in solution, as well as the valence of citric acid and citrate salts in the solid state, is essential to correctly quantify these compounds by milliequivalent (mEq) unit.
Joachim J. Hermann
core   +1 more source