Results 211 to 220 of about 42,548 (252)

Neutron and time-resolved X-ray crystallography reveal the substrate recognition and catalytic mechanism of human Nudix hydrolase MTH1. [PDF]

Proc Natl Acad Sci U S A
Hirata K, Fujimiya K, Ostermann A, Schrader TE, Hiromoto T, Goto M, Arimori T, Hirano Y, Kusaka K, Tamada T, Nakamura T.   +10 more
europepmc   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Correction for Zhang et al., Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Engineering pH-Responsive Dendrimer-STAT3 Inhibitor Conjugates for Intracellular Delivery. [PDF]

Biomacromolecules
Siva Sankara C, Shanbhag AR, Rincón Díaz D, Hodges CA, Li C, Harrison JK, Zhang F.   +6 more
europepmc   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Societal cost-of-illness analysis of self-injection of biologics for patients with rheumatoid arthritis in Japan using claims, surveys, and national statistics. [PDF]

Health Econ Rev
Takahata K, Tanaka E, Sakai R, Akazawa M.   +3 more
europepmc   +1 more source

The Use of Enhanced Analytical Pipelines for the Characterization of Poly(A) and Poly(A)-LNP Formulation Critical Quality Attributes. [PDF]

Mol Pharm
Davidson CG, Kapsali E, Ioannou S, Kopilovic B, Hussain M, Perrie Y, Rattray Z.   +6 more
europepmc   +1 more source

Impact of Fluorine in Manganese Citrate Synthesis on Structure and Value-Added Decomposition Products. [PDF]

Molecules
Škrjanc A, Trstenjak E, Opresnik M, Gabrijelčič M, Golobič A, Zabukovec Logar N.   +5 more
europepmc   +1 more source

<i>In Vivo</i> Therapeutic Potential of Next-Generation Probiotic <i>Akkermansia muciniphila</i> and Butyrate Combination Therapy in Diabetes. [PDF]

J Microbiol Biotechnol
Ghorbanian F, Seo H, Sarafraz F, Atashi A, Shuvo MSH, Chae-Eun P, Hossain MS, Tajdozian H, Kim S, Song HY, Yang H.   +10 more
europepmc   +1 more source

Synthesis of biocompatible gold nanoparticles for photothermal therapy by mineralization using peptides. [PDF]

RSC Adv
Yoshida S, Yoshida K, Shitamukai Y, Ozaki M, Tsuruoka T, Usui K.   +5 more
europepmc   +1 more source