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Identification of the stereoisomeric configurations of methylcitric acid produced bysi‐citrate synthase and methylcitrate synthase using capillary gas chromatography‐mass spectrometry

open access: closedJournal of Inherited Metabolic Disease, 1994
SummaryThe absolute separation of the four stereoisomeric configurations of methylcitric acid can be achieved on a nonchiral stationary phase SE30 capillary column using the correspondingO‐acetylated (tri‐(−)‐2‐butyl ester derivatives. Identification of the separated isomers was done using methylcitric acid produced bysi‐citrate synthase and ...
J. P. G. van Rooyen   +6 more
openalex   +3 more sources

Citrate (si)-synthase

open access: closed, 1990
Dietmar Schomburg, Margit Salzmann
openalex   +2 more sources
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MitoQ alleviates mitochondria damage in sepsis-acute lung injury in a citrate synthase dependent manner

Inflammation Research
Sepsis is a systemic inflammatory disease caused by severe infection, involving multiple organs in the body, with the lungs being the most susceptible, leading patients to develop acute lung injury (ALI).
Jiaojiao Sun, Si-Hao Jin, Zhiqiang Wang
semanticscholar   +1 more source

Citrate synthases improve sepsis-induced lung injury by reconstructing the mitochondrial tricarboxylic acid cycle of macrophages.

Journal of Trauma and Acute Care Surgery
BACKGROUND The destruction of mitochondrial function during sepsis-induced acute lung injury can lead to tissue cell damage and organ dysfunction. Citrate synthase (CS) may maintain cellular energy metabolism by enhancing the mitochondrial tricarboxylic ...
Jiaojiao Sun, Si-Hao Jin, Zhiqiang Wang
semanticscholar   +1 more source

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