STAT3 Regulation of Citrate Synthase Is Essential during the Initiation of Lymphocyte Cell Growth [PDF]
Cell Reports, 2017 Summary: Citrate is a required carbon precursor for de novo fatty acid and membrane lipid synthesis. However, the pathways regulating intracellular citrate, particularly during the initial transition from a resting state to cell growth, remain unclear ...
Sarah MacPherson +5 more
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Allosteric role of the citrate synthase homology domain of ATP citrate lyase [PDF]
Nature Communications, 2023 ATP citrate lyase (ACLY) is the predominant nucleocytosolic source of acetyl-CoA and is aberrantly regulated in many diseases making it an attractive therapeutic target.
Xuepeng Wei +6 more
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Production of Esters in Escherichia coli Using Citrate Synthase Variants [PDF]
MicroorganismsAcetate esters comprise a wide range of products including fragrances and industrial solvents. Biosynthesis of esters offers a promising alternative to chemical synthesis because such routes use renewable carbohydrate resources and minimize the ...
Jacoby C. Shipmon +4 more
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Citrate synthase from Synechocystis is a distinct class of bacterial citrate synthase. [PDF]
Sci Rep, 2019 AbstractCitrate synthase (CS, EC 2.3.3.1) catalyses the initial reaction of the tricarboxylic acid (TCA) cycle. Although CSs from heterotrophic bacteria have been extensively studied, cyanobacterial CSs are not well-understood. Cyanobacteria can produce various metabolites from carbon dioxide. Synechocystis sp.
Ito S, Koyama N, Osanai T.
europepmc +4 more sources
Deletion of Re-citrate synthase allows for analysis of contributions of tricarboxylic acid cycle directionality to the growth of Heliomicrobium modesticaldum [PDF]
Applied and Environmental MicrobiologyHeliomicrobium modesticaldum, a phototrophic member of the phylum Firmicutes and family Clostridiales, possesses most of the enzymes specific to the reductive tricarboxylic acid (rTCA) cycle, except for the key enzyme, ATP-citrate lyase. It is thought to
Alexandria M. Layton +2 more
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Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells. [PDF]
Proteome Sci, 2022 Xu X +9 more
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Bacterial cell cycle control by citrate synthase independent of enzymatic activity [PDF]
eLife, 2020 Proliferating cells must coordinate central metabolism with the cell cycle. How central energy metabolism regulates bacterial cell cycle functions is not well understood.
Matthieu Bergé +6 more
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A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression. [PDF]
Cancer ResCheung JCT +19 more
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Is the TCA cycle malate dehydrogenase-citrate synthase metabolon an illusion? [PDF]
Essays BiochemOmini J +4 more
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β-Hydroxybutyrate and Citrate Synthase as Potential Diagnostic Biomarkers in Aging-Related Atrial Fibrillation. [PDF]
J Cardiovasc Transl ResHe JK +7 more
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