Knockdown of prohibitin 2 promotes apoptosis in non-small cell lung cancer cell line A549 [PDF]
Jichu yixue yu linchuang, 2023 Objective To explore mechanism of prohibitin 2(PHB2) inhibition on the apoptosis of non-small cell lung cancer cell line A549. Methods For stable knockdown of PHB2, A549 strain was infected with lentiviruses. A549 cells with PHB2 depletion were
ZHANG Jing, YANG Zigeng, WEI Hongmei, NING Haihong, XUE Xixi, JIN Ling, WU Bin
doaj +1 more source
Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. [PDF]
PLoS ONE, 2017 Reduced cellular ATP synthesis due to impaired mitochondrial function of immune cells may be a factor influencing the immune response in septic shock. We investigate changes in mitochondrial function and bioenergetics of human monocytes and lymphocyte ...
Tobias M Merz +6 more
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The Klebsiella pneumoniae citrate synthase gene, gltA, influences site specific fitness during infection. [PDF]
PLoS Pathog, 2019 Vornhagen J +6 more
europepmc +3 more sources
Altered Oxygen Utilisation in Rat Left Ventricle and Soleus after 14 Days, but Not 2 Days, of Environmental Hypoxia. [PDF]
, 2015 The effects of environmental hypoxia on cardiac and skeletal muscle metabolism are dependent on the duration and severity of hypoxic exposure, though factors which dictate the nature of the metabolic response to hypoxia are poorly understood.
Burgess, Sarah L. +3 more
core +9 more sources
Engineered citrate synthase improves citramalic acid generation in Escherichia coli
Biotechnology and Bioengineering, 2020 The microbial product citramalic acid (citramalate) serves as a five‐carbon precursor for the chemical synthesis of methacrylic acid. This biochemical is synthesized in Escherichia coli directly by the condensation of pyruvate and acetyl‐CoA via the ...
Xianghao Wu +2 more
semanticscholar +1 more source
Sustainability, 2020 Yarrowia lipolytica is a non-conventional yeast producing valuable compounds, such as citric acids, from renewable raw materials. This study investigated the impact of citrate synthase overexpression on the biosynthesis of citric and isocitric acid in Y.
Piotr Hapeta +5 more
semanticscholar +1 more source
The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]
, 2013 The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
A Keller +71 more
core +8 more sources
Effects of exogenous melatonin on sugar and organic acid metabolism in early-ripening peach fruits.
PLoS ONE, 2023 To evaluated the effects melatonin (MT) on the sugar and acid metabolism of early-ripening peach fruits, the concentration of 150 μmol/L MT was sprayed on the leaves of peach trees.
Kexuan Zhou +8 more
doaj +1 more source
HIF1α-dependent mitophagy facilitates cardiomyoblast differentiation [PDF]
, 2020 Mitophagy is thought to play a key role in eliminating damaged mitochondria, with diseases such as cancer and neurodegeneration exhibiting defects in this process.
Allen, George F. G. +4 more
core +3 more sources
International Brazilian Journal of Urology, 2010 PURPOSE: The etiology of obstructive bladder dysfunction includes free radical damage to mitochondria. Feeding rabbits a standardized grape suspension protects the ability of the bladder to contract and empty in part by preventing mitochondrial damage ...
Vijay Venugopal +3 more
doaj +1 more source