Results 41 to 50 of about 143,830 (347)

Implications of the expression of Enterococcus faecalis citrate fermentation genes during infection. [PDF]

open access: yesPLoS ONE, 2018
Citrate is an ubiquitous compound in nature. However, citrate fermentation is present only in a few pathogenic or nonpathogenic microorganisms. The citrate fermentation pathway includes a citrate transporter, a citrate lyase complex, an oxaloacetate ...
Gabriela P Martino   +3 more
doaj   +1 more source

Mitochondrial DNA content and mass increase in progression from normal to hyperplastic to cancer endometrium

open access: yesBMC Research Notes, 2012
Background An increase in mitochondrial DNA (mtDNA) content and mitochondrial biogenesis associated with the activation of PGC-1α signalling pathway was previously reported in type I endometrial cancer. The aim of this study has been to evaluate if mtDNA
Cormio Antonella   +10 more
doaj   +1 more source

Discrete breathers in nonlinear network models of proteins

open access: yes, 2007
We introduce a topology-based nonlinear network model of protein dynamics with the aim of investigating the interplay of spatial disorder and nonlinearity. We show that spontaneous localization of energy occurs generically and is a site-dependent process.
Juanico, Brice   +3 more
core   +5 more sources

Phosphodiesterase Type 5 Inhibitors, Sport and Doping [PDF]

open access: yes, 2017
Phosphodiesterase type 5 inhibitors (PDE5i) (e.g., sildenafil, tadalafil, vardenafil, and avanafil) are drugs commonly used to treat erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia.
Borrione, Paolo   +8 more
core   +1 more source

Changes in the microsomal proteome of tomato fruit during ripening [PDF]

open access: yes, 2019
The variations in the membrane proteome of tomato fruit pericarp during ripening have been investigated by mass spectrometry-based label-free proteomics.
De Lorenzo, Giulia   +6 more
core   +1 more source

Aggregation Prevention Assay for Chaperone Activity of Proteins Using Spectroflurometry

open access: yesBio-Protocol, 2017
The ability to stabilize other proteins against thermal aggregation is one of the major characteristics of chaperone proteins. Molecular chaperones bind to nonnative conformations of proteins.
Manish Bhuwan   +3 more
doaj   +1 more source

Purification and properties of citrate synthase from Acetobacter europaeus [PDF]

open access: yes, 2017
Citrate synthase (EC 4.1.3.7) was purified from the acidophilic bacterium Acetobacter europaeus to electrophoretic homogeneity. The specific activity was 228 units/mg of protein during the exponential ethanol-oxidation growth phase.
Sievers, Martin   +2 more
core  

Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]

open access: yes, 2018
Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J.   +14 more
core   +3 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

open access: yesAdvanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv   +10 more
wiley   +1 more source

Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity [PDF]

open access: yes, 2011
The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) enhances oxidative metabolism in skeletal muscle. Excessive lipid oxidation and electron transport chain activity can, however, lead to the accumulation of harmful metabolites and ...
Handschin, C.   +3 more
core   +1 more source

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