Results 61 to 70 of about 490,642 (236)

A statistical algorithm showing coenzyme Q10 and citrate synthase as biomarkers for mitochondrial respiratory chain enzyme activities

Scientific Reports, 2016
Laboratory data interpretation for the assessment of complex biological systems remains a great challenge, as occurs in mitochondrial function research studies.
D. Yubero, A. Adin, R. Montero, C. Jou, C. Jiménez-Mallebrera, À. García-Cazorla, A. Nascimento, M. O’Callaghan, J. Montoya, L. Gort, Plácido Navas, A. Ribes, M. Ugarte, R. Artuch   +13 more
semanticscholar   +1 more source

Relationship between wooden breast severity in broiler chicken, antioxidant enzyme activity and markers of energy metabolism

Poultry Science
: This study aims to provide new insight on the association between the development of wooden breast myopathy and mitochondrial and glycolytic activity under oxidative stress.
Binbin Li, Niina Kalmu, Xinyue Dong, Yuemei Zhang, Eero Puolanne, Per Ertbjerg   +5 more
doaj   +1 more source

C13orf31 (FAMIN) is a central regulator of immunometabolic function. [PDF]

, 2016
Single-nucleotide variations in C13orf31 (LACC1) that encode p.C284R and p.I254V in a protein of unknown function (called 'FAMIN' here) are associated with increased risk for systemic juvenile idiopathic arthritis, leprosy and Crohn's disease.

core   +2 more sources

Vitamin‐C‐dependent downregulation of the citrate metabolism pathway potentiates pancreatic ductal adenocarcinoma growth arrest

Molecular Oncology
In pancreatic ductal adenocarcinoma (PDAC), metabolic rewiring and resistance to standard therapy are closely associated. PDAC cells show enormous requirements for glucose‐derived citrate, the first rate‐limiting metabolite in the synthesis of new lipids.
Aiora Cenigaonandia‐Campillo, Ana Garcia‐Bautista, Anxo Rio‐Vilariño, Arancha Cebrian, Laura delPuerto, José Antonio Pellicer, José Antonio Gabaldón, Horacio Pérez‐Sánchez, Miguel Carmena‐Bargueño, Carolina Meroño, Javier Traba, María Jesús Fernandez‐Aceñero, Natalia Baños‐Herraiz, Lorena Mozas‐Vivar, Estrella Núñez‐Delicado, Jesús Garcia‐Foncillas, Óscar Aguilera   +16 more
doaj   +1 more source

Respiratory Muscle Training Improves Diaphragm Citrate Synthase Activity and Hemodynamic Function in Rats with Heart Failure

Brazilian Journal of Cardiovascular Surgery
INTRODUCTION: Enhanced respiratory muscle strength in patients with heart failure positively alters the clinical trajectory of heart failure. In an experimental model, respiratory muscle training in rats with heart failure has been shown to improve ...
Rodrigo Boemo Jaenisch, Mariane Bertagnolli, Audrey Borghi-Silva, Ross Arena, Pedro Dal Lago   +4 more
doaj   +1 more source

Ketogenic diet feeding improves aerobic metabolism property in extensor digitorum longus muscle of sedentary male rats.

PLoS ONE, 2020
Recent studies of the ketogenic diet, an extremely high-fat diet with extremely low carbohydrates, suggest that it changes the energy metabolism properties of skeletal muscle.
Yuji Ogura, Chiaki Kakehashi, Toshinori Yoshihara, Mitsutoshi Kurosaka, Ryo Kakigi, Kazuhiko Higashida, Sei-Etsu Fujiwara, Tatsuo Akema, Toshiya Funabashi   +8 more
doaj   +1 more source

Erectile dysfunction - an update of current practice and future strategies [PDF]

, 2013
Erectile dysfunction (ED) is defined as the inability to achieve and maintain a penile erection adequate for satisfactory sexual intercourse.1 Up to 150 million men worldwide suffer from ED and this figure is likely to double by the year 2025.2 A number
Kalsi, J, Muneer, A
core   +1 more source

Clofibrate elevates enzyme activities of the tricarboxylic acid cycle in rat liver.

Journal of Lipid Research, 1993
Activities of the tricarboxylic acid cycle enzymes were measured in subcellular fractions of liver from rats that had been fed clofibrate for 3 weeks. Large changes in these activities per gram tissue were found in the large particle fraction, which also
C Prager, HJ Schön, M Nikfardjam, D Schmid, M Untersalmberger, K Kremser, R Kramar   +6 more
doaj   +1 more source

Pre-sowing Seed Treatment with 24-Epibrassinolide Ameliorates Pesticide Stress in Brassica juncea L. through the Modulation of Stress Markers

Frontiers in Plant Science, 2016
The present experiment was designed to assess the effects of seed soaking with 24-epibrassinolide (EBR) on the physiology of Brassica juncea L. seedlings grown under imidacloprid (IMI) toxicity.
Parvaiz Ahmad, Anket Sharma, Sharad Thakur, Vinod Kumar, Mukesh Kumar Kanwar, Anup Kumar Kesavan, Ashwani Kumar Thukral, Renu Bhardwaj, Pravej Alam   +8 more
doaj   +1 more source

Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment

eLife, 2015
Evolutionary innovations that enable organisms to colonize new ecological niches are rare compared to gradual evolutionary changes in existing traits. We discovered that key mutations in the gltA gene, which encodes citrate synthase (CS), occurred both ...
Erik M. Quandt, J. Gollihar, Zachary D. Blount, A. Ellington, G. Georgiou, Jeffrey E. Barrick   +5 more
semanticscholar   +1 more source