Results 101 to 110 of about 124,247 (335)

Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study

Frontiers in Pharmacology, 2018
Polymyxins are currently used as the last-resort antibiotics against multidrug-resistant Acinetobacter baumannii. As resistance to polymyxins emerges in A. baumannii with monotherapy, combination therapy is often the only remaining treatment option.
Thien B. Tran, Thien B. Tran, Phillip J. Bergen, Darren J. Creek, Tony Velkov, Tony Velkov, Jian Li   +6 more
doaj   +1 more source

Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria [PDF]

, 2019
Methylmalonic acidemia (MMA) is a propionate pathway disorder caused by dysfunction of the mitochondrial enzyme methylmalonyl-CoA mutase (MMUT). MMUT catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA, an anaplerotic reaction which feeds into ...
Baumgartner, Matthias R, Chapman, Kimberly A, Cunningham, Gary, Forny, Patrick, Pumbo, Elena, Summar, Marshall L, Wongkittichote, Parith   +6 more
core   +1 more source

Intraspecfic variation in cold-temperature metabolic phenotypes of Arabidopsis lyrata ssp petraea [PDF]

, 2009
Atmospheric temperature is a key factor in determining the distribution of a plant species. Alongside this, plant populations growing at the margin of their range may exhibit traits that indicate genetic differentiation and adaptation to their local ...
A Suzuki, AB Bleeckerl, B Jonsell, B Usadel, B Vinocur, BH Miesak, C Alonso-Blanco, CD Thomas, CL Guy, D Cook, F Kaplan, F Kaplan, F. Ian Woodward, GR Gray, GR Walther, GR Walther, HM Lam, HM Lam, HM Lam, IC Oliveira, J Kilian, J Klotke, L Skøt, M Stitt, MA Hannah, Matthew P. Davey, MF Thomashow, MJ Clauss, MJ Clauss, MP Davey, N Smirnoff, NR Sackville Hamilton, OK Atkin, P Vergeer, RC Meyer, RJ Li, S Sagisaka, TK Peterman, W. Paul Quick, Y Zhen, Å Strand   +40 more
core   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Citric Acid Cycle Patterns in Certain Thyroid States

Journal of Biological Chemistry, 1960
(Received for publication, March 16, 1960) The “citric acid cycle” is now regarded as the final common pathway of metabolism serving as the primary route for the oxi- dation of metabolites. Likewise, the thyroid hormone is con- sidered a major regulatory substance for biological oxidations.
E C, GANGLOFF, J M, ORTEN, A H, SMITH
openaire   +2 more sources

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model. [PDF]

, 2017
In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor.
Baar, Keith, Lee-Barthel, Ann, West, Daniel WD   +2 more
core   +2 more sources

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

Advanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır, Yuan Fang, Consuelo Contreras, Andrew K. Schulz, Florian Hartmann   +4 more
wiley   +1 more source

A Comparative Study of LiNCA Cathode Recycled from Spent Lithium-Ion Batteries and Synthesized from Metal Precursor

Indonesian Journal of Chemistry
Spent lithium NCA (LiNCA) battery was recycled using organic and inorganic acids and the performances were compared against the cathode synthesized from precursor.
Arif Jumari, Enni Apriliani, Cornelius Satria Yudha, Agus Purwanto, Anne Zulfia Syahrial, Wara Dyah Pita Rengga   +5 more
doaj   +1 more source

Edible Pneumatic Battery for Sustained and Repeated Robot Actuation

Advanced Science, EarlyView.
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak, Shuhang Zhang, Alexander Keller, Qiukai Qi, Jonathan Rossiter, Dario Floreano   +5 more
wiley   +1 more source

Organic or mineral fertilization [PDF]

, 2005
To meet Swedish environmental goals organic farming will play an important role in the development of a sustainable and high quality food production system.
Heeb, Anuschka
core