Results 71 to 80 of about 124,230 (290)

Dynamics of the cellular metabolome during human cytomegalovirus infection. [PDF]

PLoS Pathogens, 2006
Viral replication requires energy and macromolecular precursors derived from the metabolic network of the host cell. Despite this reliance, the effect of viral infection on host cell metabolic composition remains poorly understood. Here we applied liquid
Joshua Munger, Sunil U Bajad, Hilary A Coller, Thomas Shenk, Joshua D Rabinowitz   +4 more
doaj   +1 more source

Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. [PDF]

, 2020
Altered metabolism in pulmonary artery smooth muscle cells (PASMCs) and endothelial cells (PAECs) contributes to the pathology of pulmonary hypertension (PH), but changes in substrate uptake and how substrates are utilized have not been fully ...
D' Alessandro, Angelo, Freeman, Scott, Graham, Brian B, Gu, Sue, Hernandez-Saavedra, Daniel, Kassa, Biruk, Kumar, Rahul, Lee, Michael H, Mickael, Claudia, Reisz, Julie A, Sanders, Linda, Stenmark, Kurt R, Tuder, Rubin M   +12 more
core   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart, Brewer, Heather M, Camp, David G, II, Depuydt, Geert, Petyuk, Vladislav A, Smith, Richard D, Smolders, Arne, Xie, Fang   +7 more
core   +2 more sources

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria [PDF]

, 2019
Methylmalonic acidemia (MMA) is a propionate pathway disorder caused by dysfunction of the mitochondrial enzyme methylmalonyl-CoA mutase (MMUT). MMUT catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA, an anaplerotic reaction which feeds into ...
Baumgartner, Matthias R, Chapman, Kimberly A, Cunningham, Gary, Forny, Patrick, Pumbo, Elena, Summar, Marshall L, Wongkittichote, Parith   +6 more
core   +1 more source

Effect of Atomic Layer Deposition of Ultra‐Thin Oxide on Reactivity and Durability of Perovskite Oxygen Electrodes

Advanced Materials, EarlyView.
This table of contents illustrates that the mechanism for mitigating Sr segregation depends strongly on the chemistry of the coating layer. HfO2 electrostatically stabilizes the surface by lowering the surface oxygen vacancies, which serve as the driving force for Sr migration. On the other hand, Al2O3 and Fe2O3 react with segregated Sr to form Sr‐Al‐O
Jongsu Seo, SungHyun Jeon, Hyunseung Kim, San Kwak, DongHwan Oh, Bonjae Koo, Jinwook Kim, Jeong Hwan Kim, WooChul Jung   +8 more
wiley   +1 more source

Composition and reversibility of fouling on low-pressure membranes in the filtration of coagulated water: insights into organic fractions behaviour [PDF]

, 2016
The primary problem for the application of microfiltration (MF) and ultrafiltration (UF) membrane technology is membrane fouling. Such is the case that understanding membrane fouling has become one of the major factors driving MF and UF membrane ...
Bernat Camí, Xavier, Ferrer Mallén, Olga, Gibert Agulló, Oriol, Lefevre, Benoit, Paraira Cardona, Miquel, Prats, Guillem   +5 more
core   +2 more sources

Freeform Manufacturing of Plant‐Based Structural Colors for Scalable Photonic and Mechanochromic Devices

Advanced Materials, EarlyView.
A green, freeform manufacturing approach that utilizes robust aqueous two‐phase systems to create intricate and scalable photonic structures and non‐planar mechanochromic hydrogel actuators from plant‐based hydroxypropyl cellulose. This approach broadens the structural possibilities of sustainable photonic devices and mechanochromic systems, offering ...
Xiao Song, Peiqi Niu, Wenxi Gu, Chun Lam Clement Chan, Jiuhong Yi, Xu Liu, Peng Tan, Chon In Haydn Cheong, Qingwen Guan, Dan Fang, Bingpu Zhou, Zi Liang Wu, Ji Liu, Yan Yan Shery Huang, Iek Man Lei   +14 more
wiley   +1 more source

Data‐Driven Discovery of Quaternary Ammonium Interlayers for Efficient and Thermally Stable Perovskite Solar Cells

Advanced Materials, EarlyView.
An active learning framework, grounded in independently generated in‐house experimental data, enables reliable discovery of high‐performance interfacial materials for perovskite solar cells. Iterative model refinement autonomously converges toward structurally robust quaternary ammonium architectures, establishing a new design principle for interfacial
Jongbeom Kim, Yang Jeong Park, Chaehoon Jeon, Nahye Shin, Jaewang Park, Seungun Lee, Jino Im, Sungroh Yoon, Sang Il Seok   +8 more
wiley   +1 more source

ROS/MMP-9 mediated CS degradation in BMSC inhibits citric acid metabolism participating in the dual regulation of bone remodelling

Cell Death Discovery
It is necessary to figure out the abnormal energy metabolites at the cellular level of postmenopausal osteoporosis (PMOP) bone microenvironment. In this study, we constructed PMOP model by ovariectomy and identified 9 differential metabolites compared ...
Wacili Da, Wen Jiang, Lin Tao
doaj   +1 more source