Results 121 to 130 of about 317 (152)

Metal Ions in Longgu (Fossilized Bone) as a Natural Synergistic Network for Multi‐Target Therapy in Psychiatric Disorders

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Longgu (fossilized bone) delivers a natural synergistic network of metal ions, Ca2+, Mg2+, Zn2+, Fe, Cu, and Mn2+ that collectively targets the interconnected pathologies of anxiety, depression, and insomnia. This multi‐ion system operates through coordinated mechanisms including ionostatic balance, cross‐pathway synergy, and systemic integration ...
Sun Xiujia, Li Zhan Hua, Gao Yuanze, Liu Jing, Li Li, Zhang Chao, Kumar Ganesan, Jianping Chen   +7 more
wiley   +1 more source

Combining Phytochemical and Computational Approach on Citrus hystrix DC. (Kaffir Lime) Peel Extract: Anti‐Diabetic and Anti‐Inflammatory Activities

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Citrus hystrix DC. (kaffir lime) peel was dried and subjected to ethanolic extract. The GC‐MS analysis showed the presence of significant phyto‐ingredients. Pharmacokinetic and ADMET filters were applied to major constituents, and molecular docking, Gene Ontology (GO), and KEGG pathway enrichment analyses on mechanistic plausibility were also performed.
Malathy Soundara Rajan, Sankarganesh Palaniyandi, Swetha Sunkar   +2 more
wiley   +1 more source

Endophytic Fungi Natural Factories of Novel Bioactive Compounds

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev, Jakhongir Movlanov, Liu Wei, Wei Liu, Maksud Isokov, Santosh Kumar Bose, Fazliddin Kobilov, Zamira Djumayeva, Buston Islamov, Jamila Sherkulova, Zafar Matyakubov, Muniskhon Meylieva, Munisa Ergasheva, Diyor Abduraxmanov, Guozheng Huang, Hongchen Jiang, Kakhramon Davranov, Guohui Pan, Nigora Rustamova   +18 more
wiley   +1 more source

Classification, Structure–Activity Relationship, and Anti‐Osteoarthritis Mechanism of Natural Flavonoids

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Natural product flavonoids have a multi‐target therapeutic intervention effect on osteoarthritis. They promote autophagy and cartilage synthesis while alleviating oxidative stress, inhibiting inflammation, and inhibiting matrix degradation. By restoring OPG/RANKL balance and regulating bone metabolism, these compounds synergistically delay the ...
Haibin Wang, Shuqi Zheng, Chunlei Hua, Wanze Feng, Zengxia Liu, Yanhong Sun, Minhui Li   +6 more
wiley   +1 more source

Quantitative Structure–Activity Relationship Approaches for Exploring the Anticancer Potential of Flavonoids

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
QSAR‐based analysis of flavonoids to identify structural determinants of anticancer activity and prioritize promising candidates. ABSTRACT Flavonoids are structurally diverse polyphenolic compounds widely distributed in fruits, vegetables, grains, and beverages, with considerable potential as anticancer agents.
Mukta Gupta, Shanu Priya, Javed Ahmad, Kasim Sakran Abass, Awanish Mishra   +4 more
wiley   +1 more source

Fungicidal Efficacy of Leaf Extracts From Khaya senegalensis (Desr.) A. Juss. Irrigated With Agricultural Drainage Water and Treated With Some Fertilizer Types

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The extraction and analysis of K. senegalensis compounds for wood preservation. Air‐dried leaves are milled, soaked in ethanol, filtered, and concentrated into dried extracts. These extracts undergo HPLC for chemical profiling. The concentrated extract is applied to wood samples to test its antifungal activity, demonstrating its potential as a natural ...
Esraa A. M. Mohamed, Ahmed M. El‐Baha, Ahmed A. A. El‑Settawy, Nader D. Shetta, Abeer A. Mohamed, Mohamed Z. M. Salem   +5 more
wiley   +1 more source

Premature Ductus Arteriosus Constriction and Pulmonary Trunk Dilation in a Case of Non‐Immune Hydrops Fetalis With Trisomy 21

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Premature constriction of the ductus arteriosus accompanied by the dilation of the pulmonary trunk constitutes a rare congenital heart anomaly that may be underestimated and can result in fetal hydrops and ultimately death if not treated; therefore, it necessitates fetal post‐mortem evaluation in all cases of legal abortion or fetal death.
Nazari Mohadeseh, Hejrati Zinatosadat, Pajokh Mojde   +2 more
wiley   +1 more source

An Open‐Label Study Investigating the 5‐HT2A Receptor Occupancy of Remlifanserin (ACP‐204) With the PET Radioligand [18F]Altanserin in Healthy Male Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 9, September 2026.
Abstract Remlifanserin (ACP‐204) is a selective 5‐HT2A receptor inverse agonist that builds upon scientific findings of its structural analog, pimavanserin. This Phase 1, open‐label study in healthy adults (N = 16) describes the central 5‐HT2A receptor occupancy of remlifanserin at different doses and plasma concentrations using positron emission ...
Ethan S. Burstein, Christine Sandiego, Brian Raether, Xiaoshu Feng, Bryan Dirks, Mona Darwish, Peter Zhang, David S. Russell, Eugenii A. Rabiner, Sanjeev Pathak   +9 more
wiley   +1 more source

Exploring the Potential of Fig Leaves (Ficus carica L.): A Review of Their Valorization as Valuable Bioresources

Food Frontiers, Volume 7, Issue 5, September 2026.
Fig leaves represent an underutilized source of bioactive compounds and promising functional ingredients. Emerging extraction technologies offer powerful tools to unlock their potential through sustainable and circular valorization, while addressing key safety and regulatory considerations.
Tamara Cilia Attard, Chiara Carini, Monica Locatelli, Vincenzo Disca, Marco Arlorio   +4 more
wiley   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, Volume 3, Issue 3, Page 444-465, September 2026.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source