Results 51 to 60 of about 9,016,062 (313)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Migration View on the Demographic Development of the Almaty City
Экономика: стратегия и практика, 2023 To characterize the demographic development of a particular region, it is necessary not only to determine population growth, but also to expand the subject area of statistical demography and conduct research to identify patterns of natural renewal of the
R. U. Rakhmetova, S. A. Kaliyeva
doaj +1 more source
City of Cooper City Proclamation [PDF]
, 2013 NSU 50th Anniversaryhttps://nsuworks.nova.edu/nsudigital_proclamations/1037/thumbnail ...
City of Cooper City
core +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Intimate Partner Violence and Sexual Violence in the City of Fairbanks: Key Results from the 2011 Alaska Victimization Survey [PDF]
, 2011 This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the City of Fairbanks, which was conducted from April to June 2011, with results released on October 7, 2011 in Fairbanks.
Rosay, André B.
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
ROAD FREIGHT TRANSPORT IN THE CITY
Nauka ta progres transportu, 2008 The paper is dealt with the issues related to the organization of traffic of truck transport in logistic system of a city. The purpose of paper is consideration of the basic problems concerning the city traffic.
O. M. Horyainov, Yu. V. Buhaiev
doaj
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
THE CITY AND ITS IMAGE: DISCOURSES OF THEORETICAL UNDERSTANDING
Russian Studies in Culture and SocietyThe article is devoted to understanding the ideas that influence the understanding of the essence of the city and its image in the process of historical development.
Maria E. Kulyan-Kozionova +2 more
doaj +1 more source