Results 51 to 60 of about 8,903,381 (313)

Migration View on the Demographic Development of the Almaty City

open access: yesЭкономика: стратегия и практика, 2023
To characterize the demographic development of a particular region, it is necessary not only to determine population growth, but also to expand the subject area of statistical demography and conduct research to identify patterns of natural renewal of the
R. U. Rakhmetova, S. A. Kaliyeva
doaj   +1 more source

Intimate Partner Violence and Sexual Violence in the City of Fairbanks: Key Results from the 2011 Alaska Victimization Survey [PDF]

open access: yes, 2011
This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the City of Fairbanks, which was conducted from April to June 2011, with results released on October 7, 2011 in Fairbanks.
Rosay, André B.
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

ROAD FREIGHT TRANSPORT IN THE CITY

open access: yesNauka ta progres transportu, 2008
The paper is dealt with the issues related to the organization of traffic of truck transport in logistic system of a city. The purpose of paper is consideration of the basic problems concerning the city traffic.
O. M. Horyainov, Yu. V. Buhaiev
doaj  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

THE CITY AND ITS IMAGE: DISCOURSES OF THEORETICAL UNDERSTANDING

open access: yesRussian Studies in Culture and Society
The article is devoted to understanding the ideas that influence the understanding of the essence of the city and its image in the process of historical development.
Maria E. Kulyan-Kozionova   +2 more
doaj   +1 more source

A NATUREZA NA CIDADE: UMA ABORDAGEM A PARTIR DA PERCEPÇÃO DA POPULAÇÃO ACERCA DO JARDIM BOTÂNICO DE CURITIBA (PR) / The nature in the city: a boarding from the perception of the population concerning the botanical garden of Curitiba (PR) [PDF]

open access: yesSociedade & Natureza, 2006
Each more difficult time becomes, nowadays, to dissociate city and nature, therefore the urbanizationprocess influences and is influenced by entorno of its area of occupation, constituting half integratedwhich if would not have to apply no link to if ...
Márcio Luís Hassler
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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