Results 61 to 70 of about 1,506,188 (310)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Identity of youth of an industrial city in historical and social contexts (the case of Leninogorsk)

Историческая этнология
The article examines the formation and manifestation of the identity of the youth of an industrial city using Leninogorsk as an example. The attitude of young people towards the town is affected, above all else, by the social opportunities it provides ...
Elvira R. Kalimullina
doaj   +1 more source

Representing Iranian-Islamic Identity in Iranian Contemporary Cities Structure

Journal of Contemporary Urban Affairs, 2019
Urban identity could be considered as the result of interaction between social identity system and urbanism system. The term “Islamic City” is defined only by considering the physics of the city and reducing the concept of the city to physical elements ...
MARYAM KAMYAR, ZAHRA JAFARI SPOUREZI
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Locus branding as an element of territorial marketing of Caucasian Mineral Waters Resort towns

Современная наука и инновации
The city as a part of the socio-cultural space has its own uniqueness, which is expressed in the formation of its image. "Locus branding" (branding of the territory) is detailed by such concepts as "identity of the city", "identity of the territory ...
A. V. Baturov, V. F. Kshishnevskaya
doaj   +1 more source

Sounds of the City: Dramaturgy, Space, Identity

Critical Stages, 2021
This article offers a response to the question, “How can we think about cities within the frame of a dramaturgy of sound?” Drawing on our scholarly interest in cities, we, the authors, consider how city meanings are produced and transmitted through music
Katie Beswick, Javon Johnson
doaj  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Cultural Identity and Knowledge Creation in Cosmopolitan Cities [PDF]

SSRN Electronic Journal, 2009
ABSTRACTWe study how the city system is affected by the possibility for the members of the same cultural diaspora to interact across different cities. In so doing, we propose a simple two‐city model with two mobile cultural groups. A localized externality fosters the productivity of individuals when groups interact in a city.
PRAROLO, GIOVANNI, OTTAVIANO, GIANMARCO IREO PAOLO   +1 more
openaire   +6 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Indeliable exhibition: Yellow river boat (2018): Trap (2018) [PDF]

, 2018
This exhibition is one of two that make up a cultural and artistic exchange project with Xi'an Art Museum, Xi'an City, Shaanxi Province, China; Waikato Museum, Hamilton, NZ; and Wintec researchers (Hamilton, NZ).
Williams, Gareth C. A.
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