Results 31 to 40 of about 5,734,389 (307)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Scientific DataPublic transport operation network data serves as the foundation for urban transportation research and sustainable development planning. China operates the world’s largest public transport system, where buses and metros constitute primary urban mobility ...
Liang Wang +12 more
doaj +1 more source
Why do zoos attract crows? A comparative study from Europe and Asia
Ecology and Evolution, 2019 Crows have successfully colonized many cities, and urban zoos have been important in this process. To evaluate why zoos attract crows, we quantified crow numbers and behavior in three zoos in Europe (Debrecen, Edinburgh, Vienna) and one in Asia (Sapporo).
László Kövér +6 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Scientific ReportsAccurate measurement and verification (M&V) of energy efficiency measures (EEM) in commercial buildings is a key requirement to improve energy performance and meet sustainability goals. Research suggests a new method to M&V EEM using generalized additive
Jian Yang +5 more
doaj +1 more source
Journal of Environmental Engineering and Landscape Management, 2015 The city center planning based on the ecological security pattern of the landscape plays an important role in protecting the healthy operation of the urban ecological environment. This paper takes the city of Harbin of Heilongjiang Province as the target
Zhang Yuanjing +2 more
doaj +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Lubbock land use planning goals overview [PDF]
, 2006 The City of Lubbock has long been a community that plans. As we enter the 21st Century, reviewing the efforts of past City Council and citizen groups is critical.
City of Lubbock Planning Department
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source