Results 61 to 70 of about 73,474 (265)

Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment

Advanced Science, EarlyView.
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo, Yijuan Wang, Dengwang Chen, Yinghan Zhang, Yi Shuai, Hualiang Yao, Tao Jiang, Hang Jiang, Ming Zhong, Xiangeng Wang, Ziwei Wang, Chenchen Xu, Ajay Goel, Hoi Tang MA, Feng Gao, Xin Wang   +15 more
wiley   +1 more source

Chinese Trade Competition and Rural Mexican Migration

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT China's accession to the World Trade Organization in 2001 reshaped global trade, reducing U.S. demand for Mexican manufactured goods and weakening Mexico's manufacturing employment. This study estimates how this trade‐induced decline affected migration and employment decisions among rural Mexicans.
Zachariah Rutledge, Joaquin Mayorga
wiley   +1 more source

Identification of traffic accident risk-prone areas under low-light conditions [PDF]

Natural Hazards and Earth System Sciences, 2015
Besides other non-behavioural factors, low-light conditions significantly influence the frequency of traffic accidents in an urban environment. This paper intends to identify the impact of low-light conditions on traffic accidents in the city of Cluj ...
K. Ivan, I. Haidu, J. Benedek, S. M. Ciobanu   +3 more
doaj   +1 more source

DEVELOPMENT OF TRAM TRAFFIC IN THE CITY OF OSIJEK

Electronic Journal of the Faculty of Civil Engineering Osijek-e-GFOS, 2016
The need for the introduction of trams in Osijek in the late 19th century was largely due to the poor connectivity between the areas of the city and the growing development of the city. Tram transport was an extremely important step in connecting and modernizing the city and a key step in the integration of the still unconnected areas of the city, a ...
Dimter, Sanja, Tanasić, Zoran, Zagvozda, Martina, Ruška, Filip   +3 more
openaire   +6 more sources

Trump Tariffs 2.0: Assessing the Impacts on US Distilled Spirits Imports

Agribusiness, EarlyView.
ABSTRACT The proposed 25% tariff on Mexico and Canada could have significant repercussions on US imports of distilled spirits. This study estimates US import demand across various spirit categories (e.g., tequila, whiskey) and assesses the potential impact of the proposed tariff.
Andrew Muhammad
wiley   +1 more source

When the River Runs Low: Heterogeneous Impacts of Transportation Disruptions on Local Grain Basis

Agribusiness, EarlyView.
ABSTRACT A substantial share of U.S. soybean and corn exports from the Midwest moves by barge along the Mississippi River system to export terminals in the Louisiana Gulf. Transportation costs between Midwestern grain elevators and export terminals create a wedge between prices at these locations, and shocks to these costs are partially passed on to ...
Yuan Zhang, Andrew E. Anderson, Nicholas J. Pates, Eunchun Park   +3 more
wiley   +1 more source

An Empirical Investigation of Speed Patterns on S-Curves Using Naturalistic Driving Data and Mixed Logit Model

Journal of Advanced Transportation
S-curves are common and complex curves in road networks, consisting of two curves in opposite directions connected by a short segment. Drivers’ behavior on S-curves reflects their ability to navigate complex environments, which is not yet fully ...
Cailin Lei, Yu Shen, Yuxiong Ji, Xiaoyu Cai, Yuchuan Du   +4 more
doaj   +1 more source

A Capacity Modelling Study of Diverging Areas in Urban Tunnels Under Intelligent Connected Environments

Promet (Zagreb)
With the advancement of connected automated vehicles (CAVs), their increasing presence in traffic flows is expected to reshape road capacity. In urban tunnels, diverging areas are essential for traffic efficiency and safety.
Xiaoyu CAI, Yudong BAI, Bo PENG, Cailin LEI, Yanping WANG   +4 more
doaj   +1 more source

Lidar‐Based Object Tracking of Traffic Participants with Sensor Nodes in Existing Urban Infrastructure

Advanced Intelligent Systems, EarlyView.
This paper presents a lidar‐based sensor node design and a rule‐based state observer for edge‐based traffic participant tracking. Unlike other state‐of‐the‐art methods, this state observer enables real‐time, CPU‐only edge processing without relying on machine learning approaches.
Simon Schäfer, Bassam Alrifaee, Ehsan Hashemi   +2 more
wiley   +1 more source

Engineering Design and Application of the Autonomous-rail Rapid Transitin Yibin City

Kongzhi Yu Xinxi Jishu, 2020
In order to solve the increasing urban congestion problem, optimize the urban traffic structure and enhance the attractiveness of city, it planned seven lines, a total of 156.9 kilometers traffic network of autonomous-rail rapid transit (ART) in Yibin ...
JIANG Xiaoqing, XIAO Lei, WU Xiongtao, HU Zhengyuan, LI Shupei, HE Jie   +5 more
doaj