Results 161 to 170 of about 42,594 (265)

Enhancing Strength and Ductility of Rubberized Concrete Using Low-Cost Glass Jackets. [PDF]

open access: yesPolymers (Basel)
Saingam P   +7 more
europepmc   +1 more source

Translating Blue Light Stimulation From Batch to Perfusion: Process and Intracellular Metabolic Analysis

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Improving cell‐specific productivity remains a central objective in biopharmaceutical manufacturing. In this study, the effect of blue light illumination on IgG1‐producing CHO DP‐12 cells was systematically evaluated across batch, fed‐batch, and perfusion cultivations in controlled 3 L bioreactor systems.
Stefanie Föller   +2 more
wiley   +1 more source

Polycationic Peptide Engineering of Phage Endolysins Expands Host Range and Enhances Antibacterial and Antibiofilm Activities Against Bacillus Species

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The exponential rise in antimicrobial resistance has highlighted the urgent need for the development of alternative antibacterial strategies, including phage‐derived and engineered protein agents such as endolysins and artilysins. In this study, we report the rational design, expression, and functional characterization of novel artilysins ...
Farhat Ansari, Tarushi, Vandan Nagar
wiley   +1 more source

Modeling Multiscale Architecture of Biofilm Extracellular Matrix and Its Role in Oxygen Transport

open access: yesBiotechnology and Bioengineering, EarlyView.
Conceptual ‘resistance‐in‐series' model using cell‐capsule approach is introduced to investigate oxygen transport in the extracellular matrix. Bacterial capsule as a separate, distinct feature from the bulk EPS is the main focus of our present study. ABSTRACT The extracellular polymeric substances (EPS) matrix of microbial biofilms exhibits a complex ...
Raghu K. Moorthy, Eoin Casey
wiley   +1 more source

A comparative study of modified performance based plastic design methods for seismic design of RC frames: improvement over existing methods. [PDF]

open access: yesSci Rep
Vyas R   +10 more
europepmc   +1 more source

Revisiting the Carbon Footprint of Single‐Use Technologies in Biomanufacturing: A Bottom‐Up Analysis Reveals a Paradigm Shift

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The biopharmaceutical industry increasingly relies on single‐use technologies (SUT) for operational flexibility. For a long time, SUT was considered more sustainable than stainless‐steel (SST) systems due to water and energy savings. This study re‐evaluates this paradigm via a detailed bottom‐up analysis of the SUT carbon footprint at the 2000 
Jan Reiners   +4 more
wiley   +1 more source

LLM‐Guided Parameter Optimization for Mechanistic CHO Cell Bioreactor Models

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Mechanistic models of Chinese Hamster Ovary (CHO) cell cultures are essential for efficient bioprocess development and control, yet parameter estimation remains a critical challenge in model calibration. As model complexity increases, the number of parameters grows and their values become highly system‐specific due to biological variability ...
Han Bit Kim   +4 more
wiley   +1 more source

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