Results 141 to 150 of about 3,483,527 (302)

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Civil appeal on brazilian Civil Procedure Code of 2015

, 2018
This article approaches the innovations brought by the new Brazilian`s Code of Civil Procedure to the civil appeal, wich is an important instrument to ensure de right to a double degree of jurisdiction. It will discourse about the whole appeal, since its
Souza, Carlos Alexandre de
core  

A Method for Optical Quantification of Local Oxygen Limitations in Multiphase Bioreactors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Spatial oxygen limitation is a major source of physiological stress and metabolic, scale‐dependent heterogeneity in aerobic bioprocesses. In gas‐liquid stirred tank reactors, oxygen availability is governed by hydrodynamics and mass transfer and is therefore inherently non‐uniform.
Ryan Rautenbach, Katharina Zörner, Jonas Barczyk, Marko Hoffmann, Ralf Takors, Michael Schlüter   +5 more
wiley   +1 more source

Natural Person’s Legal Competence in the Conception of the Assumed Civil Code [PDF]

The person’s civil ability, having as constitutive elements the capacity to have rights and obligations and the legal competence, assigns the juridical capacity specific to the civil law. While the civil capacity to have rights and obligations represents
Bojinca, Moise
core  

Comparative Analysis of Bioreactor Design and Scale‐Up for Cultivated Meat Using Monte Carlo‐Based Timescale Modeling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cultivated meat offers a sustainable alternative to conventional livestock production but faces significant scale‐up challenges, particularly in bioreactor design for mammalian cell suspension cultures. This study presents a comparative analysis of stirred tank reactors (STR), bubble columns (BC), and airlift reactors (ALR) to assess their ...
Pieter Jan Theodoor Brorens, Marcel Ottens, Cees Haringa   +2 more
wiley   +1 more source

Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt, Richard Strasser, Christopher P. Garnham, Rima Menassa   +3 more
wiley   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Practical dilemmas and communication reconstruction of patients' right to informed consent under the Civil Code. [PDF]

Front Public Health
Chen J, Ye L.
europepmc   +1 more source

Puerto Rico’s Civil Code 2020 from the Perspective of Comparative Law

El artículo analiza, desde la perspectiva del derecho comparado, cuánto contribuye el nuevo Código Civil de Puerto Rico al desarrollo y consolidación del sistema jurídico romanístico, al reafirmar su pertenencia a la tradición del derecho romano, y cómo ...
Esborraz, David Fabio
core   +4 more sources

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source