Results 231 to 240 of about 1,834,764 (288)

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu, Igor Koop, Gavin Murugan, Thagshanen Thillairajah, Karen M. Polizzi   +4 more
wiley   +1 more source

Long-Acting Technologies to Prevent HIV: Why Is the Asia-Pacific Being Left Behind? [PDF]

J Int AIDS Soc
Khwairakpam G, Thomas C, Karunanithy A, Janamnuaysook R, Nalinikanta R, South Asia and South‐East Asia (SASEA) Partnership Platform.   +5 more
europepmc   +1 more source

Addressing Small Data Challenges in Biopharmaceutical Development and Manufacturing: A Mini Review of Multi‐Fidelity Techniques

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal, Uwe Aickelin, Ellen Otte   +2 more
wiley   +1 more source

Beyond reproductive rights: implementing the Africentric reproductive justice framework in sexual and reproductive health and rights litigations in Africa. [PDF]

Sex Reprod Health Matters
Mulumba M, Oga J, Muhumuza N.
europepmc   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source

Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Interspecies cross‐reactive protein therapeutics that target conserved epitopes across species are critical for translational research. The present study showcases the engineering of an affibody molecule, originally discovered for binding to human death receptor 5 (hDR5) with 94 nM affinity, to simultaneously acquire cross‐reactivity to murine
Tse‐Han Kuo, Nagamani Vunnam, Jonathan N. Sachs, Benjamin J. Hackel   +3 more
wiley   +1 more source

Thermodynamic Evaluation of Dual Substrate Growth

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Various C₁–C₂ compounds are increasingly available through electrochemical reduction of CO2. Although not always suitable as a sole substrate, these compounds can supplement a primary substrate like glucose to enhance microbial growth. Yet, the mechanisms underlying the effects of dual substrate consumption on growth rate and growth yield ...
Marit A. Verheijen, Tim Meyboom, Mark C. M. van Loosdrecht, Rebeca Gonzalez‐Cabaleiro   +3 more
wiley   +1 more source

Civil society perspectives on tuberculosis care for people living with HIV in Brazil: A study informed by Social Representations Theory. [PDF]

PLOS Glob Public Health
Magnabosco GT, de Paulo Pedroso F, Palmieri IGS, de Souza LB, Sesnik HH, Soares Turquino SN, Lomes da Cruz KA, Nabas RM, do Carmo Antonio H, Resende MVF, Pavinati G.   +10 more
europepmc   +1 more source

Turkish Thoracic Society Declaration on Peace and Health the Importance of Breathing in a World Without War. [PDF]

Thorac Res Pract
Çetinkaya PD, Töreyin ZN, Yüce Özdemir H, Yasin Y, Kılınç O, Yorgancıoğlu A, Çalışır HC, Çuhadaroğlu Ç, Köktürk N, Demirdöğen E, Öcal N, Bingöl Z, Gürün Kaya A, Esendağlı D, Yıldız E, Balcan MB, Çil B, Kılıçgün H, Begiç E.   +18 more
europepmc   +1 more source