Results 51 to 60 of about 92,936 (187)

Cahiers de civilisation médiévale 59/1 (fascicule 233)

open access: yes, 2016
  Parution du dernier numéro des Cahiers de civilisation médiévale, Le fascicule 233, livraison de printemps du tome 59 est disponible.
Cahiers de civilisation médiévale
core   +1 more source

Renouvellement épistémologique, interdisciplinarité et modélisation de la recherche en civilisation. Rééquilibrer les perspectives et les savoirs en études civilisationnelles

open access: yesFlamme
La discipline civilisation, établie il y a plus de cinquante années, peine toujours à fonder sa légitimité. Plutôt que d’invalider son existence, ce constat peut mener à penser qu’elle résiste bien, dans la durée, à des forces contraires.
André MAGORD
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Cahiers de civilisation médiévale 57/2 (fascicule 226)

open access: yes, 2014
Parution du dernier numéro des Cahiers de civilisation médiévale. Le fascicule 226, livraison d'été du t. 57 est disponible.
Cahiers de civilisation médiévale
core   +1 more source

Cahiers de civilisation médiévale 57/3 (fascicule 227)

open access: yes, 2014
Parution du dernier numéro des Cahiers de civilisation médiévale. Le fascicule 227, livraison d'automne du t. 57 est disponible.
Cahiers de civilisation médiévale
core   +1 more source

Cahiers de civilisation médiévale 56 de 2013 (fascicule 224 bis)

open access: yes, 2016
Parution du dernier numéro des Cahiers de civilisation médiévale, Le fascicule 224 bis, livraison de 2013 du tome 56 est disponible.
Cahiers de civilisation médiévale
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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