Results 61 to 70 of about 92,936 (187)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Cahiers de civilisation médiévale 56/2 (fascicule 222)
, 2013 Parution du dernier numéro des Cahiers de civilisation médiévale.
Cahiers de civilisation médiévale
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Cahiers de civilisation médiévale 59/2 (fascicule 234)
, 2016 Parution du dernier numéro des Cahiers de civilisation médiévale, Le fascicule 234, livraison d'été du tome 59 est disponible.
Cahiers de civilisation médiévale
core +1 more source
International Journal of Islamic KhazanahThe West's view of Muslim women is not devoid of attitudes that relegate them to a kind of inferiority, as enslaved and humiliated, whose main task is to reproduce, educate, cook, wash and so on.
Mohammed Houmine
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Cahiers de civilisation médiévale 65 (fascicule 259)
, 2023 Le dernier numéro des Cahiers de civilisation médiévale, 65e année, numéro 259, juillet-septembre 2022 est paru. Sommaire Raphaël Guesuraga, Figurer l’hérésie simoniaque et la fornication cléricale. Le programme grégorien de la Porte des Comtes
Cahiers de civilisation médiévale
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Methods of Communication between Muslim Parents and Teenagers in Malaysia
IslamiyyatThe communication process within a family typically has parents as transmitters and parents as receivers. The pattern of communication between parents and children determines the family climate, whether positive or otherwise.
Zulkefli Aini +4 more
doaj +1 more source