Results 71 to 80 of about 9,594 (241)

The characterization of AD/PART co-pathology in CJD suggests independent pathogenic mechanisms and no cross-seeding between misfolded Aβ and prion proteins

Acta Neuropathologica Communications, 2019
Current evidence indicating a role of the human prion protein (PrP) in amyloid-beta (Aβ) formation or a synergistic effect between Aβ and prion pathology remains controversial. Conflicting results also concern the frequency of the association between the
Marcello Rossi, Hideaki Kai, Simone Baiardi, Anna Bartoletti-Stella, Benedetta Carlà, Corrado Zenesini, Sabina Capellari, Tetsuyuki Kitamoto, Piero Parchi   +8 more
doaj   +1 more source

Resolving Micrometre‐Scale Zircon Growth in Silicic Systems by 7 μm LA‐MC‐ICP‐MS U‐Pb Dating: Linking Petrology and Geochronology in Silicic Volcanic and Granitic Rocks from Victoria, Australia

Geostandards and Geoanalytical Research, EarlyView.
Key Points 7 μm spot‐diameter LA‐MC‐ICP‐MS analyses yield accurate zircon U‐Pb ages. 1013 Ω amplifier resistors improve low‐signal Pb measurements. Saturn correction protocols minimise down‐hole fractionation effects. We present a systematic evaluation of high spatial‐resolution zircon U‐Pb dating using a Thermo Scientific Neoma multi‐collector ICP‐MS ...
Cristiano Lana, John D. Clemens
wiley   +1 more source

UK Infected Blood Inquiry–An Historical Appraisal

Haemophilia, EarlyView.
ABSTRACT Introduction This appraisal considers the 2018 UK Infected Blood Inquiry and its Report (2024) in the context of the history of haemophilia treatment developments over the past fifty‐five years, and the tragic impacts of the AIDS pandemic. Aim The paper appraises the conduct and findings of the IBI and its Report in relation to HIV and AIDS ...
Christopher A. Ludlam
wiley   +1 more source

Primary progressive aphasia with focal periodic sharp wave complexes: An unusual manifestation of Creutzfeldt-Jakob disease

Clinical Neurophysiology Practice
Background: Creutzfeldt-Jakob disease (CJD) is a devastating degenerative brain disorder caused by an abnormal isoform of a cellular glycoprotein which is known as the prion protein. A diagnosis of CJD is usually based on specific clinical signs, EEG and
Amayak Broutian, Yuliya Shpilyukova, Alexandra Belyakova-Bodina, Anna Abramova, Olga Korepina, Rodion Konovalov   +5 more
doaj   +1 more source

A Corticobasal Syndrome Variant of Familial Creutzfeldt-Jakob Disease with Stroke-Like Onset

Case Reports in Neurological Medicine, 2016
Creutzfeldt-Jakob disease (CJD) is an untreatable rare human prion disease characterized by rapidly progressive dementia along with various neurological features, including myoclonus and sometimes other movement disorders.
Ján Necpál, Martin Stelzer, Silvia Koščová, Michal Patarák   +3 more
doaj   +1 more source

The randomized controlled trial Fast Track multilevel intervention for children with early‐emerging conduct problems breaks intergenerational transmission of violence across three generations

Journal of Child Psychology and Psychiatry, EarlyView.
Background Domestic violence mechanisms are frequently transmitted across generations, representing a global issue demanding particular attention. This study investigates the intergenerational transmission of intimate partner violence (IPV) and parent‐to‐child violence (PCV) and whether participating in a multilevel preventive intervention (Fast Track)
Laura Gorla, W. Andrew Rothenberg, Jennifer Godwin, Conduct Problems Prevention Research Group, Karen L. Bierman, John D. Coie, D. Max Crowley, Kenneth A. Dodge, Mark T. Greenberg, Jennifer E. Lansford, John E. Lochman, Robert J. McMahon, Ellen E. Pinderhughes   +12 more
wiley   +1 more source

093 CJD and motor neuron disease: a growing association [PDF]

, 2021
Adam P Cooper, Wilson Vallat
openalex   +1 more source

Understanding the Best Nutritional Management for Creutzfeldt–Jakob Disease Patients: A Comparison Between East Asian and Western Experiences

Life
(1) Background: Creutzfeldt–Jakob disease (CJD) is a rare and fatal neurodegenerative disorder caused by the accumulation of an altered prion protein, which usually leads to death within one year after clinical onset.
Alessia Perna, Massimo Santoro, Elisa Colaizzo   +2 more
doaj   +1 more source

Could Sporadic Creutzfeldt-Jakob Disease Be Underdiagnosed in China? Experience From Four Cases

Frontiers in Neurology, 2020
Background: Creutzfeldt-Jakob Disease (CJD) is a rapidly progressive neurodegenerative disease caused by the misfolded version of the cellular prion protein.
Yi-Liu Zhang, Xiao-Mei Wu, Yang Chen, Wen-Ping Gu, Wei Lu   +4 more
doaj   +1 more source

The physiological response of juvenile diploid and triploid Arctic charr Salvelinus alpinus to exhaustive exercise

Journal of Fish Biology, EarlyView.
Abstract Triploidy is an effective tool for producing sterile fishes but often results in impaired performance in commercial aquaculture. In light of this, our study compared the physiological response to exhaustive exercise in juvenile diploid and triploid Arctic charr Salvelinus alpinus, a polar species with great potential for aquaculture.
John D. Clark, Tillmann J. Benfey
wiley   +1 more source