Results 1 to 10 of about 303,794 (143)

Storytelling for impact: the creation of a storytelling program for patient partners in research

open access: yesResearch Involvement and Engagement, 2023
Storytelling is a powerful means to evoke empathy and understanding among people. When patient partners, which include patients, family members, caregivers and organ donors, share their stories with health professionals, this can prompt listeners to ...
Leah E. Getchell   +14 more
doaj   +1 more source

Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis

open access: yesArthritis Research & Therapy, 2021
Background To investigate the effects of inhibiting histone deacetylase (HDAC) 6 on inflammatory responses and tissue-destructive functions of fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA).
Jin Kyun Park   +11 more
doaj   +1 more source

Ensuring Indigenous co-leadership in health research: a Can-SOLVE CKD case example

open access: yesInternational Journal for Equity in Health, 2023
Background Indigenous people are insightful and informed about their own health and wellness, yet their visions, strengths and knowledge are rarely incorporated into health research.
Cathy Woods   +22 more
doaj   +1 more source

The epidemiology of chronic kidney disease (CKD) in rural East Africa: A population-based study. [PDF]

open access: yes, 2020
BackgroundChronic kidney disease (CKD) may be common among individuals living in sub-Saharan Africa due to the confluence of CKD risk factors and genetic predisposition.MethodsWe ascertained the prevalence of CKD and its risk factors among a sample of 3 ...
Atukunda, Mucunguzi   +14 more
core   +2 more sources

Program Report: Can-SOLVE CKD Network Presents an Inclusive Method for Developing Patient-Oriented Research Tools

open access: yesCanadian Journal of Kidney Health and Disease, 2022
Purpose of program: Given the growing interest in patient-oriented research (POR) initiatives, there is a need to provide relevant training and education on how to engage with patients as partners on research teams. Sources of information: As part of its
Leah E. Getchell   +21 more
doaj   +1 more source

Program Report: KidneyPRO, a Web-based Training Module for Patient Engagement in Kidney Research

open access: yesCanadian Journal of Kidney Health and Disease, 2020
Purpose of report: Over the recent years, there has been increasing support and traction for patient-oriented research (POR). Such an approach ensures that health research is focused on what matters most: improving outcomes for patients. Yet the realm of
Leah Getchell   +14 more
doaj   +1 more source

Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease. [PDF]

open access: yes, 2016
Mitochondria abnormalities in skeletal muscle may contribute to frailty and sarcopenia, commonly present in patients with chronic kidney disease (CKD).
Billings, Frederic T   +9 more
core   +1 more source

CKD-506: A novel HDAC6-selective inhibitor that exerts therapeutic effects in a rodent model of multiple sclerosis

open access: yesScientific Reports, 2021
Despite advances in therapeutic strategies for multiple sclerosis (MS), the therapy options remain limited with various adverse effects. Here, the therapeutic potential of CKD-506, a novel HDAC6-selective inhibitor, against MS was evaluated in mice with ...
Daekwon Bae   +10 more
doaj   +1 more source

Primary care physicians' perceptions of barriers and facilitators to management of chronic kidney disease: A mixed methods study. [PDF]

open access: yes, 2019
BackgroundGiven the high prevalence of chronic kidney disease (CKD), primary care physicians (PCPs) frequently manage early stage CKD. Nonetheless, there are challenges in providing optimal CKD care in the primary care setting.
Abdel-Kader, Khaled   +15 more
core   +1 more source

Defining the Scope of Knowledge Translation Within a National, Patient-Oriented Kidney Research Network

open access: yesCanadian Journal of Kidney Health and Disease, 2021
Purpose of program: Integrated knowledge translation (IKT) is a collaborative approach whereby knowledge created through health research is utilized in ways that are relevant to the needs of all stakeholders. However, research teams have limited capacity
Meghan J. Elliott   +13 more
doaj   +1 more source

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