Results 281 to 290 of about 343,907 (366)

Gut microbiota and the kidney-gut-skin axis in chronic kidney disease-associated pruritus: mechanisms and therapeutic implications. [PDF]

Front Cell Infect Microbiol
Chen S, Liu J, Ni H, Zhu F, Liu H, Lin R.   +5 more
europepmc   +1 more source

Preoperative Anemia and Perioperative Outcomes in Children: Prevalence, Risk Factors, and Associations in an Australian Cohort

Pediatric Anesthesia, EarlyView.
ABSTRACT Aims Preoperative anemia is a potentially modifiable risk factor in children undergoing surgery, but contemporary data describing its prevalence and associated outcomes in high‐income settings are limited. We aimed to determine the prevalence of anemia in a pediatric major‐surgery surgical cohort, identify associated demographic and clinical ...
Matthew Hart, Alexandra Batinic, Justin Skowno   +2 more
wiley   +1 more source

TAVR vs. SAVR in Patients With Severe Aortic Stenosis and Chronic Kidney Disease Undergoing Dialysis: A Comprehensive Meta-Analysis. [PDF]

Cardiol Res Pract
Mylavarapu M, Kiyani M, Tanwar N, Reddy M, Garcia I, Karnan N, Rao NL, Kodali LSM, Borra N.   +8 more
europepmc   +1 more source

Urinary Collagen Peptides Predict Mortality

PROTEOMICS, EarlyView.
ABSTRACT Organ fibrosis caused by the presence of excessive extracellular matrix (ECM) is related to mortality. Urinary peptide signatures were reported to be predictive of death in SARS‐CoV‐2 and chronic kidney disease. Such signatures were composed for 68% of collagen fragments.
Maria Frantzi, Felix Keller, Agnieszka Latosinska, Joachim Beige, Alexandre Mebazaa, Anaïs Caillard, Dewei An, Paul Perco, Joost P. Schanstra, Lorenzo Catanese, Ralph Wendt, Harald Rupprecht, Jan A. Staessen, Antonia Vlahou, Harald Mischak, Justyna Siwy   +15 more
wiley   +1 more source

Diabetic Foot Ulceration in Dialysis-Dependent End-Stage Kidney Disease: A Systematic Review of Epidemiology, Clinical Outcomes and Mortality Risk. [PDF]

Diabetes Metab Res Rev
Lim JZM, Selvarajah D, Mitra S, Ng NSL, Rayman G, Vileikyte L, Game FL, Boulton AJM.   +7 more
europepmc   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

The role of gut dysbiosis in endocrine and metabolic derangements of chronic kidney disease: mechanisms, controversies, and future perspectives. [PDF]

Front Endocrinol (Lausanne)
Ouyang Z, Hu W, Zhu F, Zhang Y, Wang L, Ye Q.   +5 more
europepmc   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola, Aislinn O'Kane, Michael Heathman, Hannah Marotta, Hayley Trussel, Bobbie Ray, Shelley Dowden, Andrea R. Masters, David M. Haas, Sara K. Quinney   +9 more
wiley   +1 more source

Temporal trends and disparities in mortality among US adults with chronic kidney disease and comorbid depression: a population-based analysis, 1999-2023. [PDF]

Front Public Health
Zhao P, Yang L, Wu F, Li Y, He Y.
europepmc   +1 more source