Results 1 to 10 of about 297,512 (353)

Sustained human outbreak of a new MPXV clade I lineage in eastern Democratic Republic of the Congo

Nature Medicine
Background: Monkeypox virus (MPXV) attracted global attention in 2022 during a widespread outbreak linked primarily to sexual contact. Clade I MPXV is prevalent in Central Africa and characterized by severe disease and high mortality, while Clade II is ...
Eddy Kinganda-Lusamaki, Edyth Parker, Isabel Brosius   +2 more
exaly   +2 more sources

Metagenomic microbial community profiling using unique clade-specific marker genes

Nature Methods, 2012
Metagenomic shotgun sequencing data can identify microbes populating a microbial community and their proportions, but existing taxonomic profiling methods are inefficient for increasingly large data sets.
Nicola Segata, Levi Waldron, Vagheesh M Narasimhan   +2 more
exaly   +2 more sources

Emergence of Clade Ib Monkeypox Virus—Current State of Evidence [PDF]

Emerging Infectious Diseases
Mpox was first identified against the backdrop of the smallpox eradication campaign. Monkeypox virus (MPXV), the causative agent of mpox, has been maintained in animal reservoirs in the forested regions of West and Central Africa as 2 distinct clades ...
Panayampalli S. Satheshkumar, Crystal M. Gigante, Placide Mbala-Kingebeni, Yoshinori Nakazawa, Mark Anderson, Stephen Balinandi, Sophia Mulei, James Fuller, Jennifer H. McQuiston, Andrea M. McCollum, Christina L. Hutson   +10 more
doaj   +2 more sources

Prediction of SARS-CoV-2 Variant Lineages Using the S1-Encoding Region Sequence Obtained by PacBio Single-Molecule Real-Time Sequencing

Viruses, 2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the causal agent of the COVID-19 pandemic that emerged in late 2019. The outbreak of variants with mutations in the region encoding the spike protein S1 sub-unit that can make them more
Sébastien Lhomme, Justine Latour, Nicolas Jeanne, Pauline Trémeaux, Noémie Ranger, Marion Migueres, Gérald Salin, Cécile Donnadieu, Jacques Izopet   +8 more
doaj   +1 more source

Clade I–Associated Mpox Cases Associated with Sexual Contact, the Democratic Republic of the Congo

Emerging Infectious Diseases, 2023
We report a cluster of clade I monkeypox virus infections linked to sexual contact in the Democratic Republic of the Congo. Case investigations resulted in 5 reverse transcription PCR–confirmed infections; genome sequencing suggest they belonged to the ...
E. M. Kibungu, E. H. Vakaniaki, E. Kinganda-Lusamaki, Thierry Kalonji-Mukendi, Elisabeth Pukuta, N. Hoff, Isaac I. Bogoch, Muge Cevik, Gregg S Gonsalves, Lisa E. Hensley, N. Low, Souradet Y. Shaw, Erin Schillberg, Mikayla Hunter, Lygie Lunyanga, Sylvie Linsuke, J. Madinga, M. Peeters, Jean-Claude Makangara Cigolo, S. Ahuka-Mundeke, J. Muyembe, A. Rimoin, J. Kindrachuk, P. Mbala-Kingebeni, R. S. Lushima   +24 more
semanticscholar   +1 more source

Intercontinental Movement of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4 Virus to the United States, 2021

Emerging Infectious Diseases, 2022
We detected Eurasian-origin highly pathogenic avian influenza A(H5N1) virus belonging to the Gs/GD lineage, clade 2.3.4.4b, in wild waterfowl in 2 Atlantic coastal states in the United States.
S. Bevins, S. Shriner, J. C. Cumbee, Krista E. Dilione, Kelly E. Douglass, Jeremy W. Ellis, M. Killian, M. Torchetti, J. Lenoch   +8 more
semanticscholar   +1 more source

Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020

Emerging Microbes and Infections, 2021
Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected ...
N. Lewis, A. Banyard, E. Whittard, Talgat Karibayev, Thamer Al Kafagi, Ilya Chvala, A. Byrne, Saduakassova Meruyert Akberovna, Jacqueline King, T. Harder, C. Grund, S. Essen, S. Reid, A. Brouwer, N. Zinyakov, Azimkhan Tegzhanov, V. Irza, Anne Pohlmann, M. Beer, R. Fouchier, Sultanov Akhmetzhan Akievich, I. Brown   +21 more
semanticscholar   +1 more source

Diversity in the Circulation of Influenza A(H3N2) Viruses in the Northern Hemisphere in the 2018–19 Season

Vaccines, 2021
While vaccination is considered the most effective means to prevent influenza infection, its seasonal effectiveness varies, depending on the circulating influenza strains.
Rakefet Pando, Shahar Stern, Ital Nemet, Aharona Glatman-Freedman, Hanna Sefty, Neta S. Zuckerman, Yaron Drori, Nehemya Friedman, John W. McCauley, Lital Keinan-Boker, Ella Mendelson, Rodney S. Daniels, Michal Mandelboim   +12 more
doaj   +1 more source

Confirmation of fifth Candida auris clade by whole genome sequencing

Emerging Microbes and Infections, 2022
Candida auris has emerged globally as a multidrug-resistant pathogen causing outbreaks in health care facilities. Whole genome sequencing (WGS) analysis has identified four major clades, while earlier WGS data from a single Iranian isolate suggested the ...
Bram Spruijtenburg, H. Badali, M. Abastabar, H. Mirhendi, S. Khodavaisy, Joobin Sharifisooraki, M. Armaki, Theun de Groot, J. Meis   +8 more
semanticscholar   +1 more source

Genomic Diversity of SARS-CoV-2 in Algeria and North African Countries: What We Know So Far and What We Expect?

Microorganisms, 2022
Here, we report a first comprehensive genomic analysis of SARS-CoV-2 variants circulating in North African countries, including Algeria, Egypt, Libya, Morocco, Sudan and Tunisia, with respect to genomic clades and mutational patterns. As of December 2021,
Taha Menasria, Margarita Aguilera
doaj   +1 more source