Results 111 to 120 of about 482,160 (387)

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

Advanced Science, EarlyView.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong, Jun Song, Shihan Li, Lu Jin, Qi He, Baohui Zhang, Yan Cao, Shanyong Yi, Yanfang Yang, Xiang Li, Juan Li, Wei Huang   +11 more
wiley   +1 more source

Novel Reassortant Clade 2.3.4.4 Avian Influenza A(H5N8) Virus in Wild Aquatic Birds, Russia, 2016

Emerging Infectious Diseases, 2017
The emergence of novel avian influenza viruses in migratory birds is of concern because of the potential for virus dissemination during fall migration. We report the identification of novel highly pathogenic avian influenza viruses of subtype H5N8, clade
Dong‐Hun Lee, K. Sharshov, D. Swayne, O. Kurskaya, I. Sobolev, Marsel R Kabilov, A. Alekseev, V. Irza, A. Shestopalov   +8 more
semanticscholar   +1 more source

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

Advanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács, Durga Prasad, Vic De Roo, Matthias Vanheede, Penthip Muangkaew, Annemieke Madder, Monica Höfte, René De Mot, Niels Geudens, José C. Martins   +9 more
wiley   +1 more source

Dimorphic enantiostyly and its function for pollination by carpenter bees in a pollen‐rewarding Caribbean bloodwort

American Journal of Botany, EarlyView.
Abstract Premise Flowers that present their anthers and stigma in close proximity can achieve precise animal‐mediated pollen transfer, but risk self‐pollination. One evolutionary solution is reciprocal herkogamy. Reciprocity of anther and style positions among different plants (i.e., a genetic dimorphism) is common in distylous plants, but very rare in
Steven D. Johnson, Jeremy J. Midgley, Luis G. Bocourt‐Hernandez, F. G. Loiret, Patricia Ortega‐Rodés, Nicola Illing   +5 more
wiley   +1 more source

Primate phylogeny: molecular evidence for a pongid clade excluding humans and a prosimian clade containing tarsiers [PDF]

, 2009
Interpretations of molecular data by the modern evolution theory are often sharply inconsistent with paleontological results. This is to be expected since the theory is only true for microevolution and yet fossil records are mostly about macroevolution.
Shi Huang
core   +1 more source

Molecular surveillance of influenza A virus in Saudi Arabia: whole-genome sequencing and metagenomic approaches

Microbiology Spectrum
Outbreaks of influenza A viruses are generally seasonal and cause annual epidemics worldwide. Due to their frequent reassortment and evolution, annual surveillance is of paramount importance to guide vaccine strategies.
Iman Dandachi, Abdulrahman Alrezaihi, Dashty Amin, Nurah AlRagi, Bader Alhatlani, Abdulwahab Binjomah, Kholoud Aleisa, Xiaofeng Dong, Julian A. Hiscox, Waleed Aljabr   +9 more
doaj   +1 more source

Phylogenomics, ecomorphological evolution, and historical biogeography in Deuterocohnia (Bromeliaceae: Pitcairnioideae)

American Journal of Botany, EarlyView.
Abstract Premise Species of Deuterocohnia (17 spp.) show extraordinary variation in elevation (0–3900 m a.s.l.) and growth forms, and many have narrow geographic distributions in the west‐central Andes and the Peru‐Chile coast. Previous research using few plastid and nuclear loci failed to produce well‐resolved or supported phylogenies.
Bing Li, Nicole Schütz, Kurt Weising, Georg Zizka, Jacob B. Landis, Thomas J. Givnish   +5 more
wiley   +1 more source

Crinoid phylogeny: a preliminary analysis (Echinodermata: Crinoidea) [PDF]

, 2004
We describe the first molecular and morphological analysis of extant crinoid high-level inter-relationships. Nuclear and mitochondrial gene sequences and a cladistically coded matrix of 30 morphological characters are presented, and analysed by ...
Ameziane, N., Cohen, B.L., De Forges, B.R., Eleaume, M.   +3 more
core   +2 more sources

Phylogenomics reveals the evolution of floral traits associated with pollinators and pollinator–prey conflict within the carnivorous Pinguicula subgenus Temnoceras

American Journal of Botany, EarlyView.
Abstract Premise The carnivorous plant genus Pinguicula (Lentibulariaceae) exhibits remarkable floral diversity associated with pollination, particularly in the largest subgenus Temnoceras, which spans Mexico and Central America. Despite this diversity, the relationships between species and the evolution of key floral traits remain unresolved. Here, we
Yunjia Liu, Qianshi Lin, Steven J. Fleck, Martín Mata‐Rosas, Enrique Ibarra‐Laclette, Tanya Renner   +5 more
wiley   +1 more source

Delimitation of Major Lineages within \u3cem\u3eCuscuta\u3c/em\u3e Subgenus \u3cem\u3eGrammica\u3c/em\u3e (Convolvulaceae) using Plastid and Nuclear DNA Sequences [PDF]

, 2007
Subgenus Grammica, the largest and most diverse group in the parasitic genus Cuscuta, includes ~130 species distributed primarily throughout the New World, with Mexico as its center of diversity.
Costea, Mihai, Kuzmina, Maria, Stefanović, Saša   +2 more
core   +1 more source