Results 191 to 200 of about 397,970 (301)

An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial. [PDF]

Nat Commun
Deming ME, Toapanta FR, Pasetti M, Golding H, Khurana S, Hamouda T, Fattom A, Liang Y, Tennant SM, McGilvray MF, Bernal PJ, Oshinsky JJ, Datta S, Booth JP, Coughlan L, Neuzil KM, Costley CD, Kotloff KL, Sztein MB, Ortiz JR, rH5 Writing Group.   +20 more
europepmc   +1 more source

Actin Isovariant ACT2‐Mediated Cellular Auxin Homeostasis Regulates Lateral Root Organogenesis in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Lateral root (LR) organogenesis is regulated by cellular flux of auxin within pericycle cells, which depends on the membrane distribution and polar localization of auxin carrier proteins. The correct distribution of auxin carrier proteins relies on the intracellular trafficking of these proteins aided by filamentous actin as a track.
Aya Hanzawa, Arifa Ahamed Rahman, Abidur Rahman   +2 more
wiley   +1 more source

Identification of SARS-CoV-2 3CLpro inhibitors from marine actinomycetes through integrated phylogeny-based metabolomics with functional screening and bioinformatic analysis. [PDF]

Sci Rep
Dalisay DS, Mateo JC, Teodosio JJR, Jusa LMS, Baladjay DMS, de Guzman LS, Balida LAP, Jamal JA.   +7 more
europepmc   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Sporulation Abilities and Heat Resistance of <i>Clostridium perfringens</i> Strains Isolated from French Food Borne Outbreaks. [PDF]

Foods
Firmesse O, Maladen V, Bourelle W, Federighi M, Tran C, Mtimet N.   +5 more
europepmc   +1 more source

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

Cytoskeleton, EarlyView.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

Relative contributions of the ERG11^VF125AL and MRR1A^N647T mutations to fluconazole resistance in Clade III Candidozyma (Candida) auris clinical isolates. [PDF]

Clin Microbiol Infect
Barker KS, Zhang Q, Peters TL, Rybak JM, Morschhäuser J, Cuomo CA, Rogers PD.   +6 more
europepmc   +1 more source

Toward the Bioremediation of Nylon Waste Materials: Genome Mining Leads to the Identification of a Thermostable Laurolactamase From Thermopolyspora flexuosa

ChemSusChem, EarlyView.
To enhance nylon waste remediation, genome mining was used to identify a thermostable laurolactam hydrolase from Thermopolyspora flexuosa with activity against an important cyclic nylon derivative. Substrate scope analysis and structural modeling revealed key features controlling enzyme‐substrate compatibility, providing a promising foundation for ...
Maria E. Cleveland, Amir R. Bunyat‐zada, Esther R. Hoffman, Graeme W. Howe   +3 more
wiley   +1 more source

First imported cases of MPXV Clade Ib from Goma, Democratic Republic of the Congo. [PDF]

Commun Med (Lond)
Mukadi-Bamuleka D, Kinganda-Lusamaki E, Mulopo-Mukanya N, Amuri-Aziza A, O'Toole Á, Merritt S, Modadra-Madakpa B, Mutombo-Ndongala G, Vakaniaki EH, Kacita C, Maboko GL, Makangara-Cigolo JC, Ngimba M, Lokilo-Lofiko E, Pukuta-Simbu E, Luakanda-Ndelemo G, Bodisa-Matamu T, Paluku-Kalimuli Z, Akil-Bandali P, Kavira-Bapitani S, Jansen D, Kavira-Kamaliro A, Muhindo-Milonde E, Mufungizi J, Birindwa-Hamisi Y, Kavunga H, Tshiani O, Nundu SS, Liesenborghs L, Hoff NA, Halbrook M, Shongo R, Ayouba A, Pilarowski G, Mangolopa AK, Ebondo AK, Low N, Shaw SY, Wilkinson S, Tessema SK, Subissi L, Delaporte E, Vercauteren K, Wawina-Bokalanga T, Rimoin AW, Hensley LE, Peeters M, Loman N, Rambaut A, Muyembe-Tamfum JJ, Kindrachuk J, Mbala-Kingebeni P, Ahuka-Mundeke S.   +52 more
europepmc   +1 more source

Sediment‐stressed reefs over the past 420 Myr

The Depositional Record, EarlyView.
In order to fully elucidate the relationship between siliciclastic sedimentation and reef development, there needs to be a significant step change in how we record ancient and recent reefs. Only through the collection of constrained quantitative data, we can progress beyond the largely conjectural associations postulated for many ancient reefal systems.
Tanja Unger, Stephen W. Lokier, Markus Aretz, Matthieu Saillol, Adrian Immenhauser   +4 more
wiley   +1 more source