Results 51 to 60 of about 334,920 (299)

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

open access: yesAdvanced Science, EarlyView.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li   +6 more
wiley   +1 more source

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

open access: yesAdvanced Science, EarlyView.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan   +5 more
wiley   +1 more source

Grass functional traits reflect the long history of fire and grazers in the savannas of Texas

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Understanding relationships among grass traits, fire, and herbivores may help improve conservation strategies for savannas that are threatened by novel disturbance regimes. Emerging theory, developed in Africa, emphasizes that functional traits of savanna grasses reflect the distinct ways that fire and grazers consume biomass ...
Ashish N. Nerlekar   +2 more
wiley   +1 more source

The phylogeny of Anophelinae revisited: inferences about the origin and classification of Anopheles (Diptera: Culicidae) [PDF]

open access: yes, 2016
© 2015 Royal Swedish Academy of Sciences. "This is the pre-peer reviewed version of the following article: Harbach, R. E. and I. J. Kitching (2016). "The phylogeny of Anophelinae revisited: inferences about the origin and classification of Anopheles ...
Harbach, RE, Kitching, I
core   +1 more source

Does the abiotic environment influence the distribution of flower and fruit colors?

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Color in flowers and fruits carries multiple functions, from attracting animal partners (pollinators, dispersers) to mitigating environmental stress (cold, drought, UV‐B). With research historically focusing on biotic interactions as selective agents, however, it remains unclear whether abiotic stressors impact flower and fruit colors ...
Agnes S. Dellinger   +3 more
wiley   +1 more source

Comparative pathogenicity of vaccinia virus and mpox virus infections in CAST/EiJ mice: Exploring splenomegaly and transcriptomic profiles

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We successfully constructed CAST/EiJ mice models infected with low‐dose vaccinia virus (VACV‐L), high‐dose VACV (VACV‐H), and mpox virus (MPXV), demonstrating that VACV‐L and MPXV infections induced splenomegaly in mice, and VACV‐H infection caused mortality in mice.
Yongzhi Hou   +9 more
wiley   +1 more source

From WGS to gels: Development and testing of PCR primers targeting toxic Digitalis in support of food safety

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise This study capitalized on a library of single‐nucleotide polymorphisms created via whole genome sequencing (WGS) to develop and test a PCR assay for detecting toxic Digitalis species in food products. Complex foods can be difficult to analyze, but safeguarding consumer well‐being and public health necessitates that products regulated ...
Elizabeth Sage Hunter   +5 more
wiley   +1 more source

A new genus, Desertispora, and a new species, Diversispora sabulosa, in the family Diversisporaceae (order Diversisporales, subphylum Glomeromycotina) [PDF]

open access: yes, 2018
Phylogenetic analyses of sequences of the SSU-ITS-LSU nrDNA segment and the RPB1 gene showed that the arbuscular mycorrhizal fungus originally described as Diversispora omaniana does not belong to the genus Diversispora, but represents a separate clade ...
Al-Yahya’ei, Mohamed N.   +4 more
core   +2 more sources

Advancing phylogenomics in Amaranthaceae sensu stricto: Development and application of a new nuclear target enrichment bait set

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Current phylogenies of Amaranthaceae sensu stricto (s.s.) are inadequately sampled and resolved to reflect the entire evolutionary history of the lineage, which is likely complex due to at least three whole‐genome duplication events, occasionally followed by subsequent additional polyploidization events and rapid diversification of ...
Tina Kiedaisch   +3 more
wiley   +1 more source

Delimitation of Major Lineages within \u3cem\u3eCuscuta\u3c/em\u3e Subgenus \u3cem\u3eGrammica\u3c/em\u3e (Convolvulaceae) using Plastid and Nuclear DNA Sequences [PDF]

open access: yes, 2007
Subgenus Grammica, the largest and most diverse group in the parasitic genus Cuscuta, includes ~130 species distributed primarily throughout the New World, with Mexico as its center of diversity.
Costea, Mihai   +2 more
core   +1 more source

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