Results 71 to 80 of about 397,970 (301)
Fibril Structure of Desiccation‐Protective Tardigrade Protein CAHS‐8
Angewandte Chemie, EarlyView.We present the atomic structure of the fibril formed by an intrinsically disordered protein that has been shown to be responsible for remarkable environmental stress in tardigrades. X‐ray crystallography reveals a unique mechanism of fibril assembly whereby a single helix forms a stable, antiparallel coiled‐coil dimer, which then assembles into a ...
Anas Malki +6 more
wiley +2 more sources
mSphere, 2018 The difficulties related to virus taxonomy have been amplified by recent advances in next-generation sequencing and metagenomics, prompting the field to revisit the question of what constitutes a useful viral classification.
Gary R. Whittaker +2 more
doaj +1 more source
Analysis of the timing of freely falling antihydrogen
New Journal of Physics, 2022 We evaluate the accuracy to be expected for the measurement of free fall acceleration of antihydrogen in the GBAR experiment, accounting for the recoil transferred in the photodetachment process. We show that the uncertainty on the measurement of gravity
Olivier Rousselle +4 more
doaj +1 more source
Virulence Traits and Azole Resistance in Korean Candida auris Isolates
Journal of Fungi, 2023 We analyzed the virulence traits and azole resistance mechanisms of 104 Candida auris isolates collected from 13 Korean hospitals from 1996 to 2022. Of these 104 isolates, 96 (5 blood and 91 ear isolates) belonged to clade II, and 8 (6 blood and 2 other ...
Seung A. Byun +11 more
doaj +1 more source
Discrete and continuous character-based disparity analyses converge to the same macroevolutionary signa. A case study from captorhinids [PDF]
, 2017 The relationship between diversity and disparity during the evolutionary history of a clade provides unique insights into evolutionary radiations and the biological response to bottlenecks and to extinctions.
Brocklehurst, Neil +2 more
core +2 more sources
Advanced Therapeutics, EarlyView.This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack +13 more
wiley +1 more source
Emerging Microbes and Infections, 2021 In South Africa, Candida auris was the third most common cause of candidemia in 2016–2017. We performed single nucleotide polymorphism (SNP) genome-wide analysis of 115 C.
Serisha D. Naicker +6 more
doaj +1 more source
Advanced Science, EarlyView.This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen +31 more
wiley +1 more source
Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C. [PDF]
PLoS Pathogens, 2016 We have investigated the immunogenicity in rabbits of native-like, soluble, recombinant SOSIP.664 trimers based on the env genes of four isolates of human immunodeficiency virus type 1 (HIV-1); specifically BG505 (clade A), B41 (clade B), CZA97 (clade C)
P J Klasse +16 more
doaj +1 more source
Global Diversification Rates of Ferns Across Spatial and Climatic Gradients
Advanced Science, EarlyView.Diversification rates of fern genera across the phylogeny. Abstract Geographic patterns of diversity in any group of plants are the result of the interplay of environmental conditions and the evolutionary dynamics of the respective plant group. Here, the geographic distribution of current mean diversification rates (MDR) is explored at the genus level ...
Hong Qian, Michael Kessler, Shenhua Qian
wiley +1 more source