Results 71 to 80 of about 310,389 (304)

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

open access: yesAdvanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing   +10 more
wiley   +1 more source

Enhanced analysis of the genomic diversity of Mycobacterium bovis in Great Britain to aid control of bovine tuberculosis

open access: yesFrontiers in Microbiology
Bovine tuberculosis (bTB) is an endemic disease in Great Britain (GB) that affects mainly cattle but also other livestock and wild mammal species, leading to significant economic and social impact. Traditional genotyping of Mycobacterium bovis (M. bovis)
Prizam Sandhu   +10 more
doaj   +1 more source

Lost and Found: Return of the Inverted Repeat in the Legume Clade Defined by Its Absence

open access: yesGenome Biology and Evolution, 2019
The plant genome comprises a coevolving, integrated genetic system housed in three subcellular compartments: the nucleus, mitochondrion, and the plastid.
In-Su Choi, R. Jansen, Tracey A Ruhlman
semanticscholar   +1 more source

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

open access: yesAdvanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu   +15 more
wiley   +1 more source

An overview on the phylogenetic classification of Brucella

open access: yesRevista U.D.C.A Actualidad & Divulgación Científica, 2018
The genus Brucella is a globally distributed intracellular pathogen that affects animals and humans and presents low genetic variability, which is a challenge for its phylogenetic reconstruction.
Juana Vidal, Luisa Ortiz, Martha Olivera
doaj   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects

open access: yesMemorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Human herpesvirus 2 (HHV-2) have DNA genome with a limited genetic variability and have been classified into two clades. OBJECTIVES To identify and characterise six HHV-2 isolates derived from Brazilian women.
Lyana Rodrigues Pinto Lima   +5 more
doaj   +1 more source

Insights into the Unique Nature of the East Asian Clade of the Emerging Pathogenic Yeast Candida auris

open access: yesJournal of Clinical Microbiology, 2019
The emerging yeast Candida auris can be highly drug resistant, causing invasive infections, and large outbreaks. C. auris went from an unknown pathogen a decade ago to being reported in over thirty countries on six continents. ABSTRACT The emerging yeast
R. Welsh   +4 more
semanticscholar   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

open access: yesAdvanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao   +6 more
wiley   +1 more source

PirVP genes causing AHPND identified in a new Vibrio species (Vibrio punensis) within the commensal Orientalis clade

open access: yesScientific Reports, 2018
Acute hepatopancreatic necrosis disease (AHPND) has extended rapidly, causing alarming shrimp mortalities. Initially, the only known causative agent was Vibrio parahaemolyticus carrying a plasmid coding for the mortal toxins PirVP.
Leda Restrepo   +6 more
semanticscholar   +1 more source

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