Results 81 to 90 of about 310,389 (304)

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Characterization of a novel reassortant H5N6 highly pathogenic avian influenza virus clade 2.3.4.4 in Korea, 2017

Emerging Microbes and Infections, 2018
Dear Editor, Highly pathogenic avian influenza (HPAI) viruses of the H5 subtype remain a serious concern for both poultry and human health. The clade 2.3.4.4 H5 viruses have evolved into four genetic groups (nominally designated A, B, C, and D).
Eun-Kyoung Lee, Y. Lee, S. Kye, N. Lewis, I. Brown, M. Sagong, Gyeong-Beom Heo, Yong-Myung Kang, Hyun-Kyu Cho, Hyunmi Kang, Sun-Ha Cheon, Myeongheon Lee, B. Park, Yong-Joo Kim, Youn-Jeong Lee   +14 more
semanticscholar   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

Molecular surveillance of influenza A virus in Saudi Arabia: whole-genome sequencing and metagenomic approaches

Microbiology Spectrum
Outbreaks of influenza A viruses are generally seasonal and cause annual epidemics worldwide. Due to their frequent reassortment and evolution, annual surveillance is of paramount importance to guide vaccine strategies.
Iman Dandachi, Abdulrahman Alrezaihi, Dashty Amin, Nurah AlRagi, Bader Alhatlani, Abdulwahab Binjomah, Kholoud Aleisa, Xiaofeng Dong, Julian A. Hiscox, Waleed Aljabr   +9 more
doaj   +1 more source

Multi‐Targeting Non‐Specific Genome Engineering in Bacteria

Advanced Science, EarlyView.
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun, Ruixiang You, Yiwen Zhou, Huiyan He, Wenfang Wang, Xudong Qu, Yinhua Lu, Lei Li   +7 more
wiley   +1 more source

Expansion of a urethritis-associated Neisseria meningitidis clade in the United States with concurrent acquisition of N. gonorrhoeae alleles

BMC Genomics, 2018
BackgroundIncreased reports of Neisseria meningitidis urethritis in multiple U.S. cities during 2015 have been attributed to the emergence of a novel clade of nongroupable N. meningitidis within the ST-11 clonal complex, the “U.S. NmNG urethritis clade”.
Adam C. Retchless, C. Kretz, J. Bazan, Jeanine A Abrams, C. Kretz, How-Yi Chang, A. J. Abrams, A. N. Turner, Laurel T Jenkins, D. Trees, Yih-Ling Tzeng, D. Stephens, Jessica R Macneil, Xin Wang   +13 more
semanticscholar   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

The Genomic Basis of Parasitism in the Strongyloides Clade of Nematodes

Nature Genetics, 2016
Soil-transmitted nematodes, including the Strongyloides genus, cause one of the most prevalent neglected tropical diseases. Here we compare the genomes of four Strongyloides species, including the human pathogen Strongyloides stercoralis, and their close
Vicky L. Hunt, Isheng. J. Tsai, Avril Coghlan, A. Reid, Nancy E. Holroyd, B. Foth, A. Tracey, J. Cotton, Eleanor Stanley, H. Beasley, H. Bennett, K. Brooks, Bhavana Harsha, Rei Kajitani, A. Kulkarni, D. Harbecke, Eiji Nagayasu, S. Nichol, Yoshitoshi Ogura, M. Quail, N. Randle, D. Xia, N. Brattig, Hanns Soblik, D. Ribeiro, A. Sánchez-Flores, Tetsuya Hayashi, T. Itoh, D. Denver, W. Grant, Jonathan D. C. Stoltzfus, J. Lok, H. Murayama, J. Wastling, A. Streit, T. Kikuchi, M. Viney, M. Berriman   +37 more
semanticscholar   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Molecular Characterization of Indonesian Indigenous Chickens based on Mitochondrial DNA Displacement (D)-loop Sequences

Hayati Journal of Biosciences, 2008
The Mitochondrial DNA (mtDNA) displacement (D)-loop sequences were used to study the genetic diversity and relationship of Indonesian indigenous chickens.
SRI SULANDARI, MOCH SYAMSUL ARIFIN ZEIN, TIKE SARTIKA   +2 more
doaj