Results 101 to 110 of about 557,404 (343)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A 28GHz, Switched-Cascode, Class E Amplifier in 22nm CMOS FDSOI Technology

IEEE Journal of Microwaves
Using the stacking technique in CMOS technology for Power Amplifiers (PAs), allows the use of a higher supply voltage. This facilitates achieving a higher voltage swing, and delivering more output power while maintaining a high efficiency.
Nourhan Elsayed, Saeedeh Makhsuci, Mihai Sanduleanu   +2 more
doaj   +1 more source

Analysis and Optimized Design of Metamaterials for Mid-Range Wireless Power Transfer Using a Class-E RF Power Amplifier

Applied Sciences, 2018
In this paper, a mid-range wireless power transfer (WPT) system based on metamaterials (MMs) has been presented. It has been shown that the MMs are positioned in the WPT system to focalize the electromagnetic field for distance enhancement and efficiency
Cancan Rong, Xiong Tao, Conghui Lu, Zhaoyang Hu, Xiutao Huang, Yingqin Zeng, Minghai Liu   +6 more
doaj   +1 more source

Optimization Of 5.7 Ghz Class E Power Amplifier For The Application Of Envelope Elimination And Restoration [PDF]

, 2015
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2007Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2007Rekabetin yoğun olduğu günümüzde tasarımcılar hafif, boyutları daha küçük ve düşük
Yumak, F. Figen
core  

A second-order class-D audio amplifier [PDF]

, 2011
Class-D audio amplifiers are particularly efficient, and this efficiency has led to their ubiquity in a wide range of modern electronic appliances. Their output takes the form of a high-frequency square wave whose duty cycle (ratio of on-time to off-time)
Jun Yu, Mellor P. H., Meng Tong Tan, Stephen M. Cox, Tan M. T.   +4 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RF power generation

, 2011
This paper reviews the main types of r.f. power amplifiers which are, or may be, used for particle accelerators. It covers solid-state devices, tetrodes, inductive output tubes, klystrons, magnetrons, and gyrotrons with power outputs greater than 10 kW c.
Carter, R. G.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Systematic Design of a Compact Lumped-Element Outphasing Class-E Power Amplifier for HF Band

IEEE Access
This paper presents a novel design methodology for an outphasing Class-E power amplifier operating at 27.12 MHz, specifically addressing limitations inherent to traditional outphasing combiners that utilize distributed microstrip transmission lines for ...
Khairul Hilmi Yusof, Farid Zubir, Mohamad Kamal A. Rahim, Narendra Kumar, Jagadheswaran Rajendran, Noorlindawaty Md Jizat, Peter Gardner, Thomas Johnson   +7 more
doaj   +1 more source