Results 51 to 60 of about 33,505,955 (241)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Analysis of operation of class E ZVS resonant inverter [PDF]
, 2005 The article discusses class E zero-voltage-switching resonant inverter (ZVS). The resonant circuit of the inverter is subject to mathematical analysis using the method of state variables with the aid of MATLAB software.
Szychta, E.
core
IEEE AccessThis paper presents an analysis and design of the load-independent (LI) high-frequency magnetic resonant wireless power transfer (MR-WPT) system with robustness against load variations and coil misalignments.
Yutaro Komiyama +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Design, simulation and commissioning of a 5-level CHB Inverter [PDF]
, 2022 openQuesto elaborato presenta uno studio su un inverter Cascaded H-bridge (CHB) a cinque livelli. L’inverter è composto da due moduli H-bridge in cascata; con questa configurazione è possibile ottenere cinque livelli di tensione in uscita utilizzando ...
DE MICHIEL, ALDO
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Carga eletrônica ativa trifásica [PDF]
, 2013 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2013.Neste trabalho estão apresentados os estudos efetuados do conversor trifásico bidirecional de três níveis
Heerdt, Joselito Anastácio
core
Generalized Average Model of the Class-E2 DC-DC Resonant converter
Eletrônica de PotênciaIn this paper, the generalized average model of the Class-E$^2$ DC-DC resonant converter has been introduced. The standard average model is not interesting in resonant converters due to their large waveform oscillations.
Lucas S. Mendonça, Fábio Ecke Bisogno
doaj +1 more source