Results 111 to 120 of about 1,459,552 (317)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Topics in computational group theory : primitive permutation groups and matrix group normalisers
, 2012 Part I of this thesis presents methods for finding the primitive permutation groups of degree d, where 2500 ≤ d < 4096, using the O'Nan-Scott Theorem and Aschbacher's theorem. Tables of the groups G are given for each O'Nan-Scott class.
Coutts, Hannah Jane
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Negotiation and Navigation - an Exploration of the Spaces/Places of Working-Class Lesbians [PDF]
This article draws upon my research on working-class lesbians, which explores the relationship between class, sexuality and social exclusion. Research participants were drawn mainly from Scotland (Glasgow, Edinburgh and the Highlands), with smaller ...
Yvette Taylor
core
A presentation of the mapping of class groups [PDF]
Mathematical Research Letters, 1997 Using the works of Gervais, Harer, Hatcher and Thurston and others, we show that the mapping class group of a compact orientable surface has a presentation so that the generators are the set of all Dehn twists and the relations are supported in subsurfaces homeomorphic to the one-holed torus or the four-holed sphere. It turns out that all the relations
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Centralisers of finite subgroups in soluble groups of type FPn
, 2009 We show that for soluble groups of type FPn , centralisers of finite subgroups need not be of type ...
Martínez-Pérez, Conchita +5 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Class groups of large ranks in biquadratic fields
summary:For any integer $n>1$, we provide a parametric family of biquadratic fields with class groups having $n$-rank at least 2.
Ram, Mahesh Kumar
core +1 more source