Results 141 to 150 of about 1,459,552 (317)
National Journal of Community Medicine, 2016 Background: Self help groups provide a critical outlet for building more sustainable socioeconomic status. They have emerged as support groups in facing all kinds of problems in their domestic environment and makes a significant impact on their socio ...
Ranjitha A, Vidya GS
doaj
Defect groups of class S $$ \mathcal{S} $$ theories from the Coulomb branch
Journal of High Energy PhysicsWe study the global forms of class S A N − 1 $$ \mathcal{S}\left[{A}_{N-1}\right] $$ 4d N $$ \mathcal{N} $$ = 2 theories by deriving their defect groups (charges of line operators up to screening by local operators) from Coulomb branch data. Specifically,
Elias Riedel Gårding
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Unification and equation solving in nilpotent groups and monoids [PDF]
, 1991 Unification and equation solving have been considered for groups [44], semigroups [43], abelian groups [39] and abelian semigroups [25], [33], [68], [69]. In this thesis we consider partially commutative groups and monoids. Nilpotency provides us with a
Burke, Edmund Kieran, Burke, E.K
core
Prime order derangements in primitive permutation groups
, 2011 Let G be a transitive permutation group on a finite set Ω of size at least 2. An element of G is a derangement if it has no fixed points on Ω. Let r be a prime divisor of |Ω|.
Giudici, M. +10 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The automorphism group of a class of semi-groups
Monatshefte f�r Mathematik, 1977 Let (S,·) be a semi-group having the following properties: (1)S=∪Sα where α is in some index setI andSα are subgroups isomorphic to each other, (2)Sα∩Sβ=O, a void set for α≠β and (3) the identity ofSα is a left identity ofS for each α inI. Then the automorphism group Aut (S) ofS is studied from the point of category theory. It is proved that Aut (S) is
openaire +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source