Results 181 to 190 of about 1,251,661 (316)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

1937 Journalism II Class

, 1937
A Journalism II class standing together.

core  

Prevalence and activity of class II microcins in <i>Serratia marcescens</i> strains by isolation source. [PDF]

Appl Environ Microbiol
Parker JK, Toursarkissian LP, Chang JR, Sanchez-Paiva S, O'Donnell AC, Badmus HO, Nunez MP, Uhlemann A-C, Davies BW.   +8 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Clinical and molecular characteristics of Class II and III BRAF mutations in colorectal cancer. [PDF]

NPJ Precis Oncol
Sahin IH, Xiu J, Baca Y, Khushman M, Grothey A, Palumbo E, Rahman S, Weinberg BA, Goel S, Akce M, Gorantla V, Lou E, Kasi A, Shields AF, Oberley M, Sledge G, Shen JP, Saeed A, Tejani M.   +18 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Class II Range Land

, 1941
Photograph of two UNIDENTIED men examining a Class II Rangeland. A herd of cows is behind the barbed wire fence in background. The back of the photograph proclaims, "Class II Range Land. Grass on this range land is not thick as that on the Class I range,
Davis, David O.
core  

Herbst and Twin Block appliances in Class II malocclusion management for children: a systematic review and meta-analysis. [PDF]

Front Dent Med
Coronel-Zubiate FT, Meza-Málaga JM, Luján-Valencia SA, Marroquín-Soto C, Cruzado-Oliva F, Aguirre-Ipenza R, Luján-Urviola E, Farje-Gallardo CA, Dos Santos Pinto A, Arbildo-Vega HI.   +9 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

MHC Class II and Beyond: Complex Role of CD74 in Cancer. [PDF]

Cells
Bandola-Simon J, Roche PA.
europepmc   +1 more source