Results 201 to 210 of about 831,819 (311)

Influence of Vertical Facial Patterns on Dental Arch Parameters in Class III Malocclusions: A Cross-Sectional Study. [PDF]

Turk J Orthod
Yıldırım G, Öztürk EA, Acar YB.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Evaluation of GCF Adiponectin and Resistin Expression Level as an Indicator in Periodontal Staging and Grading After Periodontal Therapy in Class III Obese Patients. [PDF]

Int J Dent
Badr BM, Ibrahim IH, Ali AI, Hudu SA, Ali AR, Kamel AM.   +5 more
europepmc   +1 more source

Killip Class III [PDF]

, 2020
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Retraction and rotation of the mandibular arch with buccal shelf bone screws to resolve Class III skeletal malocclusion. [PDF]

Angle Orthod
Lee HT, Lin JH, Chang CH, Roberts WE.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Volume Change of Masticatory Muscles by Skeletal Class III Orthognathic Surgery with and Without Facial Asymmetry: A Cross-Sectional and Longitudinal Study. [PDF]

J Clin Med
Arima H, Tachiki C, Takaki T, Nishikawa K, Goto TK, Sueishi K, Nishii Y.   +6 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Left atrial function in class III obesity: a pilot study using two-dimensional speckle tracking echocardiography. [PDF]

BMC Cardiovasc Disord
Tudík P, Jurica J, Péč MJ, Focko B, Miertová Z, Miert A, Kubíková L, Nagy N, Lecký P, Ságová I, Bolek T, Vachalcová MB, Mokáň M, Samoš M.   +13 more
europepmc   +1 more source