Results 221 to 230 of about 831,819 (311)

Dentoskeletal changes and anteroposterior improvements in skeletal class III malocclusion treated with MEAW: A retrospective study. [PDF]

PLoS One
Tran PNQ, Cu AH, Tran MNT, Tran VNT.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Genome-wide identification and alkaline stress response analysis of the class III peroxidase (PRX) gene family in Castanea mollissima. [PDF]

BMC Plant Biol
Liu X, Zhang T, Lu G, Li Q, Zhao Y, Wang D, Wang X, Zhang G, Zhang H, Wang X, Yu L.   +10 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Comparison of Aligners and Braces in Angle's Class III Malocclusion Cases: A Clinical Study.

J Pharm Bioallied Sci
Panda B, Chaudhari DV, Nagella SP, Kudagi V, Aby DM, Datla PKV, Syed AK.   +6 more
europepmc   +1 more source

Facial esthetic perception between skeletal Class III patients treated with conventional and surgery-first orthognathic approaches. [PDF]

Angle Orthod
Cunha A, Manso T, Faber J, Artese F, Miguel JAM.   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Alicyclobacillin 24: a class III bacteriocin from <i>Alicyclobacillus acidoterrestris</i> targeting species associated with spoilage of acidic fruit-based products. [PDF]

Front Microbiol
Leonardo IC, Quendera AP, Freitas MC, Pereira Santos S, Lemos AR, Ferro Rodrigues C, Ferreira H, Sobral Pimenta M, São-José C, Bandeiras TM, Barreto Crespo MT, Bustos Gaspar F.   +11 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effectiveness of Intra-oral Non-skeletally Anchored Appliances in the Correction of Skeletal Class III Malocclusion in Growing Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Cureus
Kourbaj YM, Hajeer MY, Kara-Boulad JM, Zakaria AS, Abou Nassar JN, Alfailany DT, Alam MK.   +6 more
europepmc   +1 more source