Results 111 to 120 of about 312,758 (315)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Adjacency Labeling Schemes for Small Classes

open access: yesCoRR
A graph class admits an implicit representation if, for every positive integer $n$, its $n$-vertex graphs have a $O(\log n)$-bit (adjacency) labeling scheme, i.e., their vertices can be labeled by binary strings of length $O(\log n)$ such that the presence of an edge between any pair of vertices can be deduced solely from their labels.
Bonnet, Édouard   +3 more
openaire   +5 more sources

Performance of the apnea classification scheme using various evaluation measures for the class apnea verses class normal problem.

open access: yes, 2023
Performance of the apnea classification scheme using various evaluation measures for the class apnea verses class normal problem.
Paweł Pławiak (17328063)   +4 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

On $Q$-Polynomial Association Schemes of Small Class

open access: yesThe Electronic Journal of Combinatorics, 2012
We show an inequality involving the third largest or second smallest dual eigenvalues of $Q$-polynomial association schemes of class at least three. Also we characterize dual-tight $Q$-polynomial association schemes of class three. Our method is based on tridiagonal matrices and can be applied to distance-regular graphs as well.
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Implementation of solar UV and energetic particle precipitation within the LINOZ scheme in ICON-ART [PDF]

open access: yesGeoscientific Model Development
We extended the Linearized ozone scheme – LINOZ in the ICON (ICOsahedral Nonhydrostatic) – ART (the extension for Aerosols and Reactive Trace gases) model system to include NOy formed by auroral and medium-energy electrons in the upper mesosphere and ...
M. Ramezani Ziarani   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A class of symmetric association schemes as inclusion of biplanes

open access: yesArs Comb., 2014
Let ${\cal B}$ be a nontrivial biplane of order $k-2$ represented by symmetric canonical incidence matrix with trace $1+ \binom{k}{2}$. We proved that ${\cal B}$ includes a partially balanced incomplete design with association scheme of three classes. Consequently, these structures are symmetric, having $2k-6$ points. While it is not known whether this
openaire   +3 more sources

Using Discrete Choice Experiments to Derive Individual-Specific WTP Estimates for Landscape Improvements under Agri-Environmental Schemes: Evidence from the Rural Environment Protection Scheme in Ireland [PDF]

open access: yes
Reported in this paper are the findings from two discrete choice experiments that were carried out to address the value of a number of farm landscape improvement measures within the Rural Environment Protection (REP) Scheme in Ireland. Image manipulation
W. George Hutchinson   +2 more
core  

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