Results 151 to 160 of about 10,543,759 (362)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Comparison of pH of seminal plasma and blood serum in males and effects of female broodstocks on male sperm quality parameters in Cyprinus Carpio

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2009
This research was conducted in 2007 on Cyprinus carpi° in Alvand High School in Ghasreshirin. We randomly selected 20 broodstock male fishes in 2 age classes (2+, 3+ years old). In each year class, 10 males were selected and after sperm striping, seminal
Sh. Hosseini; R. Lorestani
doaj  

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Universal Classes of Hash Functions

open access: yesJournal of computer and system sciences (Print), 1979
L. Carter, M. Wegman
semanticscholar   +1 more source

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