Results 41 to 50 of about 19,117,049 (199)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

An Exploration of Key Issues in the Debate Between Classic and Constructivist Grounded Theory

open access: yesGrounded Theory Review: An International Journal, 2018
In this paper, the debates and discourse between Classic GT or Constructivist GT are explored. The aim of this paper is to evaluate the various claims in a critical manner by revisiting the original discourse outlining these approaches. The importance of
Anne O’ Connor   +2 more
doaj   +2 more sources

A Study on Switching Intervals in Classic DTC for Induction Motor

open access: yesIranian Journal of Electrical and Electronic Engineering, 2021
In this paper, a conceptual study on switching intervals in the classic direct torque control (DTC) method and a novel modified method have been proposed.
A. Ghayebloo, S. Shiri
doaj  

A reduced-order extrapolating collocation spectral method based on POD for the 2D Sobolev equations

open access: yesBoundary Value Problems, 2019
In this paper, we mainly use a proper orthogonal decomposition (POD) to reduce the order of the coefficient vectors of the solutions for the classical collocation spectral (CS) method of two-dimensional (2D) Sobolev equations.
Shiju Jin, Zhendong Luo
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Classic Paper Russian Text-books for Foreign Students — electronic text-books — smart text-books

open access: yesRussian Language Studies, 2014
The author considers three periods in creating Russian textbooks for foreign students: a classic paper, an electronic and a smart textbook. The author describes their specific features.
S S Khromov
doaj  

Methodological Decision-Making in Classic Grounded Theory: Preserving Emergence Without Forcing

open access: yesInternational Journal of Qualitative Methods
Classic grounded theory (Classic GT) is commonly described as an emergent methodology in which analytic direction unfolds naturally through constant comparison. While this characterisation reflects the epistemological intent of Classic GT, it can obscure
Tracy Flenady
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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